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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TUB
All Species:
35.76
Human Site:
S191
Identified Species:
71.52
UniProt:
P50607
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50607
NP_003311.2
506
55651
S191
T
M
Q
R
K
G
I
S
S
S
M
S
F
D
E
Chimpanzee
Pan troglodytes
XP_521835
552
60170
S237
T
M
Q
R
K
G
I
S
S
S
M
S
F
D
E
Rhesus Macaque
Macaca mulatta
XP_001104584
506
55633
S191
T
M
Q
R
K
G
I
S
S
S
M
S
F
E
E
Dog
Lupus familis
XP_542495
624
68661
S309
T
M
Q
R
K
G
V
S
S
S
M
S
F
E
E
Cat
Felis silvestris
Mouse
Mus musculus
P50586
505
55343
S191
T
M
Q
R
K
G
I
S
S
S
M
S
F
D
E
Rat
Rattus norvegicus
O88808
505
55299
S191
T
M
Q
R
K
G
I
S
S
S
M
S
F
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508810
461
50869
G157
P
E
G
E
G
G
V
G
N
Q
S
G
S
P
P
Chicken
Gallus gallus
XP_420992
506
56544
S194
A
M
Q
K
K
G
I
S
S
S
M
N
F
D
E
Frog
Xenopus laevis
NP_001086168
505
56501
S193
T
M
Q
K
K
G
I
S
S
S
M
N
F
D
E
Zebra Danio
Brachydanio rerio
XP_697114
530
58796
S218
T
M
L
K
K
G
I
S
S
S
M
N
F
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09306
426
48435
E131
S
C
V
V
S
D
D
E
D
E
D
K
R
S
Y
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8VY21
406
45293
I111
S
S
K
L
T
F
P
I
S
L
K
Q
P
G
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.4
99
76.9
N.A.
95.8
96.2
N.A.
53.3
77
75.3
72.2
N.A.
N.A.
N.A.
41.2
N.A.
Protein Similarity:
100
91.1
99.5
78.8
N.A.
97.6
97.4
N.A.
66.4
86.3
85.5
80.7
N.A.
N.A.
N.A.
57.9
N.A.
P-Site Identity:
100
100
93.3
86.6
N.A.
100
100
N.A.
6.6
80
86.6
80
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
93.3
100
93.3
N.A.
N.A.
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
9
9
0
9
0
9
0
0
59
0
% D
% Glu:
0
9
0
9
0
0
0
9
0
9
0
0
0
17
75
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
0
75
0
0
% F
% Gly:
0
0
9
0
9
84
0
9
0
0
0
9
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
67
9
0
0
0
0
0
0
0
% I
% Lys:
0
0
9
25
75
0
0
0
0
0
9
9
0
0
0
% K
% Leu:
0
0
9
9
0
0
0
0
0
9
0
0
0
0
0
% L
% Met:
0
75
0
0
0
0
0
0
0
0
75
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
9
0
0
25
0
0
0
% N
% Pro:
9
0
0
0
0
0
9
0
0
0
0
0
9
9
17
% P
% Gln:
0
0
67
0
0
0
0
0
0
9
0
9
0
0
0
% Q
% Arg:
0
0
0
50
0
0
0
0
0
0
0
0
9
0
0
% R
% Ser:
17
9
0
0
9
0
0
75
84
75
9
50
9
9
0
% S
% Thr:
67
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
9
9
0
0
17
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _