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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TUB
All Species:
26.97
Human Site:
S227
Identified Species:
53.94
UniProt:
P50607
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50607
NP_003311.2
506
55651
S227
S
S
A
T
S
R
K
S
V
R
E
A
A
S
A
Chimpanzee
Pan troglodytes
XP_521835
552
60170
S273
S
S
A
T
S
R
K
S
V
R
E
A
A
S
A
Rhesus Macaque
Macaca mulatta
XP_001104584
506
55633
S227
S
S
A
T
S
R
K
S
V
R
E
A
A
S
A
Dog
Lupus familis
XP_542495
624
68661
S345
S
S
A
T
S
R
K
S
T
R
E
A
A
S
A
Cat
Felis silvestris
Mouse
Mus musculus
P50586
505
55343
I227
S
A
T
S
R
K
S
I
R
E
A
A
S
A
P
Rat
Rattus norvegicus
O88808
505
55299
T227
S
A
T
S
R
K
S
T
R
E
A
A
S
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508810
461
50869
V193
S
G
C
S
A
V
P
V
P
A
A
T
A
G
T
Chicken
Gallus gallus
XP_420992
506
56544
S230
G
S
A
T
S
K
K
S
S
K
E
V
A
S
A
Frog
Xenopus laevis
NP_001086168
505
56501
S229
G
S
A
T
S
K
K
S
H
K
E
T
V
S
A
Zebra Danio
Brachydanio rerio
XP_697114
530
58796
S254
G
S
A
T
S
K
K
S
S
K
E
A
T
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09306
426
48435
L167
Y
N
F
I
K
N
N
L
A
K
F
V
E
D
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8VY21
406
45293
S147
L
G
L
N
Q
A
A
S
N
D
D
G
K
F
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.4
99
76.9
N.A.
95.8
96.2
N.A.
53.3
77
75.3
72.2
N.A.
N.A.
N.A.
41.2
N.A.
Protein Similarity:
100
91.1
99.5
78.8
N.A.
97.6
97.4
N.A.
66.4
86.3
85.5
80.7
N.A.
N.A.
N.A.
57.9
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
13.3
13.3
N.A.
13.3
66.6
60
66.6
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
46.6
53.3
N.A.
26.6
80
73.3
80
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
59
0
9
9
9
0
9
9
25
59
50
17
59
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
9
9
0
0
9
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
17
59
0
9
0
0
% E
% Phe:
0
0
9
0
0
0
0
0
0
0
9
0
0
9
0
% F
% Gly:
25
17
0
0
0
0
0
0
0
0
0
9
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
0
0
9
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
9
42
59
0
0
34
0
0
9
0
0
% K
% Leu:
9
0
9
0
0
0
0
9
0
0
0
0
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
9
0
9
9
0
9
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
9
0
9
0
0
0
0
0
25
% P
% Gln:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
17
34
0
0
17
34
0
0
0
0
0
% R
% Ser:
59
59
0
25
59
0
17
67
17
0
0
0
17
59
0
% S
% Thr:
0
0
17
59
0
0
0
9
9
0
0
17
9
0
9
% T
% Val:
0
0
0
0
0
9
0
9
25
0
0
17
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _