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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TUB
All Species:
22.73
Human Site:
S334
Identified Species:
45.45
UniProt:
P50607
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50607
NP_003311.2
506
55651
S334
S
Y
I
G
K
L
R
S
N
L
M
G
T
K
F
Chimpanzee
Pan troglodytes
XP_521835
552
60170
S380
S
Y
I
G
K
L
R
S
N
L
M
G
T
K
F
Rhesus Macaque
Macaca mulatta
XP_001104584
506
55633
S334
S
Y
I
G
K
L
R
S
N
L
M
G
T
K
F
Dog
Lupus familis
XP_542495
624
68661
S452
S
Y
I
G
K
L
R
S
N
L
M
G
T
K
F
Cat
Felis silvestris
Mouse
Mus musculus
P50586
505
55343
S333
S
Y
I
G
K
L
R
S
N
L
M
G
T
K
F
Rat
Rattus norvegicus
O88808
505
55299
S333
S
Y
I
G
K
L
R
S
N
L
M
G
T
K
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508810
461
50869
R289
G
S
Y
V
G
K
L
R
S
N
L
M
G
T
R
Chicken
Gallus gallus
XP_420992
506
56544
R334
E
S
F
I
G
K
L
R
S
N
L
M
G
T
K
Frog
Xenopus laevis
NP_001086168
505
56501
R333
E
S
F
I
G
K
L
R
S
N
L
M
G
T
K
Zebra Danio
Brachydanio rerio
XP_697114
530
58796
R358
E
S
F
I
G
K
L
R
S
N
L
M
G
T
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09306
426
48435
A255
C
A
K
V
R
S
N
A
L
G
T
Q
F
T
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8VY21
406
45293
P235
R
I
P
S
G
N
Y
P
V
A
H
I
S
Y
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.4
99
76.9
N.A.
95.8
96.2
N.A.
53.3
77
75.3
72.2
N.A.
N.A.
N.A.
41.2
N.A.
Protein Similarity:
100
91.1
99.5
78.8
N.A.
97.6
97.4
N.A.
66.4
86.3
85.5
80.7
N.A.
N.A.
N.A.
57.9
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
0
0
0
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
13.3
13.3
13.3
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
0
9
0
9
0
0
0
0
0
% A
% Cys:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
25
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% E
% Phe:
0
0
25
0
0
0
0
0
0
0
0
0
9
0
50
% F
% Gly:
9
0
0
50
42
0
0
0
0
9
0
50
34
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% H
% Ile:
0
9
50
25
0
0
0
0
0
0
0
9
0
0
0
% I
% Lys:
0
0
9
0
50
34
0
0
0
0
0
0
0
50
25
% K
% Leu:
0
0
0
0
0
50
34
0
9
50
34
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
50
34
0
0
0
% M
% Asn:
0
0
0
0
0
9
9
0
50
34
0
0
0
0
0
% N
% Pro:
0
0
9
0
0
0
0
9
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% Q
% Arg:
9
0
0
0
9
0
50
34
0
0
0
0
0
0
9
% R
% Ser:
50
34
0
9
0
9
0
50
34
0
0
0
9
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
9
0
50
42
0
% T
% Val:
0
0
0
17
0
0
0
0
9
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
50
9
0
0
0
9
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _