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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TUB All Species: 40.91
Human Site: T448 Identified Species: 81.82
UniProt: P50607 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P50607 NP_003311.2 506 55651 T448 L N F H G R V T Q A S V K N F
Chimpanzee Pan troglodytes XP_521835 552 60170 T494 L N F H G R V T Q A S V K N F
Rhesus Macaque Macaca mulatta XP_001104584 506 55633 T448 L N F H G R V T Q A S V K N F
Dog Lupus familis XP_542495 624 68661 T566 L N F H G R V T Q A S V K N F
Cat Felis silvestris
Mouse Mus musculus P50586 505 55343 T447 L N F H G R V T Q A S V K N F
Rat Rattus norvegicus O88808 505 55299 T447 L N F H G R V T Q A S V K N F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508810 461 50869 T403 L N F H G R V T Q A S V K N F
Chicken Gallus gallus XP_420992 506 56544 T448 L N F H G R V T Q A S V K N F
Frog Xenopus laevis NP_001086168 505 56501 T447 L N F H G R V T Q A S V K N F
Zebra Danio Brachydanio rerio XP_697114 530 58796 T472 L N F H G R V T Q A S V K N F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09306 426 48435 Q369 N F H G R V T Q A S V K N F Q
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8VY21 406 45293 Q349 V A S V K N F Q L V A A P E N
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.4 99 76.9 N.A. 95.8 96.2 N.A. 53.3 77 75.3 72.2 N.A. N.A. N.A. 41.2 N.A.
Protein Similarity: 100 91.1 99.5 78.8 N.A. 97.6 97.4 N.A. 66.4 86.3 85.5 80.7 N.A. N.A. N.A. 57.9 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 100 100 100 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 100 100 N.A. N.A. N.A. 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 23.9 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 38.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 0 0 0 0 9 84 9 9 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % E
% Phe: 0 9 84 0 0 0 9 0 0 0 0 0 0 9 84 % F
% Gly: 0 0 0 9 84 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 9 84 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 9 0 0 0 0 0 0 9 84 0 0 % K
% Leu: 84 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 84 0 0 0 9 0 0 0 0 0 0 9 84 9 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % P
% Gln: 0 0 0 0 0 0 0 17 84 0 0 0 0 0 9 % Q
% Arg: 0 0 0 0 9 84 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 9 0 0 0 0 0 0 9 84 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 9 84 0 0 0 0 0 0 0 % T
% Val: 9 0 0 9 0 9 84 0 0 9 9 84 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _