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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HLCS
All Species:
7.58
Human Site:
S340
Identified Species:
20.83
UniProt:
P50747
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50747
NP_000402.3
726
80760
S340
V
H
L
E
L
P
P
S
S
N
I
V
Q
T
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535590
735
81203
S349
A
H
L
E
L
P
P
S
S
S
V
V
Q
G
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q920N2
722
78498
G336
V
H
L
E
L
P
P
G
A
S
L
V
Q
T
A
Rat
Rattus norvegicus
XP_001054618
870
94843
S484
V
H
L
E
L
P
P
S
A
P
L
V
Q
T
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517245
456
48674
C81
H
P
L
H
L
S
S
C
H
E
C
L
E
L
E
Chicken
Gallus gallus
XP_416725
892
99815
N507
V
H
L
E
L
D
T
N
S
V
D
I
Q
T
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649542
1041
115906
V641
L
Q
S
G
G
K
A
V
F
S
Q
V
H
L
E
Honey Bee
Apis mellifera
XP_395226
927
105104
M545
I
H
L
E
V
D
P
M
Q
Y
E
F
E
E
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783045
948
103186
I512
K
T
K
G
G
M
A
I
F
S
Q
I
C
F
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
77
N.A.
76.7
63.9
N.A.
34.5
48.7
N.A.
N.A.
N.A.
23.6
23.9
N.A.
26.1
Protein Similarity:
100
N.A.
N.A.
85.5
N.A.
84.4
71
N.A.
43.9
63
N.A.
N.A.
N.A.
38.4
42.8
N.A.
42.7
P-Site Identity:
100
N.A.
N.A.
66.6
N.A.
66.6
73.3
N.A.
13.3
53.3
N.A.
N.A.
N.A.
6.6
26.6
N.A.
6.6
P-Site Similarity:
100
N.A.
N.A.
80
N.A.
86.6
86.6
N.A.
26.6
66.6
N.A.
N.A.
N.A.
20
46.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
0
0
23
0
23
0
0
0
0
0
12
% A
% Cys:
0
0
0
0
0
0
0
12
0
0
12
0
12
0
0
% C
% Asp:
0
0
0
0
0
23
0
0
0
0
12
0
0
0
0
% D
% Glu:
0
0
0
67
0
0
0
0
0
12
12
0
23
12
34
% E
% Phe:
0
0
0
0
0
0
0
0
23
0
0
12
0
12
0
% F
% Gly:
0
0
0
23
23
0
0
12
0
0
0
0
0
12
0
% G
% His:
12
67
0
12
0
0
0
0
12
0
0
0
12
0
0
% H
% Ile:
12
0
0
0
0
0
0
12
0
0
12
23
0
0
0
% I
% Lys:
12
0
12
0
0
12
0
0
0
0
0
0
0
0
0
% K
% Leu:
12
0
78
0
67
0
0
0
0
0
23
12
0
23
0
% L
% Met:
0
0
0
0
0
12
0
12
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
12
0
12
0
0
0
0
0
% N
% Pro:
0
12
0
0
0
45
56
0
0
12
0
0
0
0
23
% P
% Gln:
0
12
0
0
0
0
0
0
12
0
23
0
56
0
12
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
12
0
0
12
12
34
34
45
0
0
0
0
12
% S
% Thr:
0
12
0
0
0
0
12
0
0
0
0
0
0
45
12
% T
% Val:
45
0
0
0
12
0
0
12
0
12
12
56
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _