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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HLCS
All Species:
15.76
Human Site:
S355
Identified Species:
43.33
UniProt:
P50747
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50747
NP_000402.3
726
80760
S355
E
D
F
N
L
L
K
S
S
N
F
R
R
Y
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535590
735
81203
S364
E
D
F
N
L
L
K
S
S
N
L
R
R
Y
E
Cat
Felis silvestris
Mouse
Mus musculus
Q920N2
722
78498
S351
D
D
F
N
V
L
K
S
S
N
V
R
R
H
E
Rat
Rattus norvegicus
XP_001054618
870
94843
S499
D
D
F
N
V
L
K
S
S
N
T
R
R
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517245
456
48674
K96
N
S
T
I
E
S
V
K
F
A
S
A
E
D
I
Chicken
Gallus gallus
XP_416725
892
99815
M522
E
D
F
N
L
L
K
M
S
N
P
K
R
Y
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649542
1041
115906
S656
M
N
P
S
E
F
E
S
D
E
T
K
Y
S
I
Honey Bee
Apis mellifera
XP_395226
927
105104
S560
K
F
N
A
L
K
E
S
N
V
T
R
L
E
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783045
948
103186
Q527
E
G
H
L
E
G
T
Q
E
D
M
A
I
D
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
77
N.A.
76.7
63.9
N.A.
34.5
48.7
N.A.
N.A.
N.A.
23.6
23.9
N.A.
26.1
Protein Similarity:
100
N.A.
N.A.
85.5
N.A.
84.4
71
N.A.
43.9
63
N.A.
N.A.
N.A.
38.4
42.8
N.A.
42.7
P-Site Identity:
100
N.A.
N.A.
93.3
N.A.
73.3
73.3
N.A.
0
80
N.A.
N.A.
N.A.
6.6
20
N.A.
6.6
P-Site Similarity:
100
N.A.
N.A.
93.3
N.A.
93.3
86.6
N.A.
0
86.6
N.A.
N.A.
N.A.
33.3
40
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
0
0
0
0
0
12
0
23
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
23
56
0
0
0
0
0
0
12
12
0
0
0
23
0
% D
% Glu:
45
0
0
0
34
0
23
0
12
12
0
0
12
12
56
% E
% Phe:
0
12
56
0
0
12
0
0
12
0
12
0
0
0
0
% F
% Gly:
0
12
0
0
0
12
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
12
0
0
0
0
0
0
0
0
0
0
12
0
% H
% Ile:
0
0
0
12
0
0
0
0
0
0
0
0
12
0
34
% I
% Lys:
12
0
0
0
0
12
56
12
0
0
0
23
0
0
0
% K
% Leu:
0
0
0
12
45
56
0
0
0
0
12
0
12
12
0
% L
% Met:
12
0
0
0
0
0
0
12
0
0
12
0
0
0
12
% M
% Asn:
12
12
12
56
0
0
0
0
12
56
0
0
0
0
0
% N
% Pro:
0
0
12
0
0
0
0
0
0
0
12
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
56
56
0
0
% R
% Ser:
0
12
0
12
0
12
0
67
56
0
12
0
0
12
0
% S
% Thr:
0
0
12
0
0
0
12
0
0
0
34
0
0
0
0
% T
% Val:
0
0
0
0
23
0
12
0
0
12
12
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
12
34
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _