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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HLCS
All Species:
11.52
Human Site:
S685
Identified Species:
31.67
UniProt:
P50747
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50747
NP_000402.3
726
80760
S685
S
A
E
G
P
K
V
S
I
V
G
L
D
D
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535590
735
81203
W694
G
L
E
G
P
E
V
W
I
V
G
L
D
D
S
Cat
Felis silvestris
Mouse
Mus musculus
Q920N2
722
78498
S681
S
T
E
G
P
Q
A
S
I
V
G
L
D
D
S
Rat
Rattus norvegicus
XP_001054618
870
94843
S829
S
S
E
G
P
A
V
S
I
V
G
L
D
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517245
456
48674
E421
E
T
E
G
F
A
S
E
Y
F
S
M
D
T
Y
Chicken
Gallus gallus
XP_416725
892
99815
W852
N
E
E
G
P
L
A
W
I
V
G
I
D
D
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649542
1041
115906
E1000
K
D
Q
E
K
E
A
E
I
V
G
I
D
D
F
Honey Bee
Apis mellifera
XP_395226
927
105104
R888
T
G
M
T
Q
N
V
R
I
L
G
I
D
D
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783045
948
103186
T905
S
E
D
G
D
E
V
T
I
T
G
L
D
K
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
77
N.A.
76.7
63.9
N.A.
34.5
48.7
N.A.
N.A.
N.A.
23.6
23.9
N.A.
26.1
Protein Similarity:
100
N.A.
N.A.
85.5
N.A.
84.4
71
N.A.
43.9
63
N.A.
N.A.
N.A.
38.4
42.8
N.A.
42.7
P-Site Identity:
100
N.A.
N.A.
73.3
N.A.
80
86.6
N.A.
20
53.3
N.A.
N.A.
N.A.
33.3
33.3
N.A.
46.6
P-Site Similarity:
100
N.A.
N.A.
80
N.A.
86.6
93.3
N.A.
26.6
66.6
N.A.
N.A.
N.A.
53.3
53.3
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
0
0
23
34
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
12
0
12
0
0
0
0
0
0
0
100
78
0
% D
% Glu:
12
23
67
12
0
34
0
23
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
12
0
0
0
0
12
0
0
0
0
12
% F
% Gly:
12
12
0
78
0
0
0
0
0
0
89
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
89
0
0
34
0
0
0
% I
% Lys:
12
0
0
0
12
12
0
0
0
0
0
0
0
12
0
% K
% Leu:
0
12
0
0
0
12
0
0
0
12
0
56
0
0
0
% L
% Met:
0
0
12
0
0
0
0
0
0
0
0
12
0
0
0
% M
% Asn:
12
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
56
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
12
0
12
12
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% R
% Ser:
45
12
0
0
0
0
12
34
0
0
12
0
0
0
45
% S
% Thr:
12
23
0
12
0
0
0
12
0
12
0
0
0
12
12
% T
% Val:
0
0
0
0
0
0
56
0
0
67
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
23
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
34
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _