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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HLCS
All Species:
2.73
Human Site:
S83
Identified Species:
7.5
UniProt:
P50747
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50747
NP_000402.3
726
80760
S83
R
R
G
S
A
S
G
S
E
P
A
G
D
S
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535590
735
81203
G91
Q
E
E
A
G
T
S
G
S
E
P
A
E
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q920N2
722
78498
E82
R
R
R
G
C
A
P
E
S
E
P
A
A
D
G
Rat
Rattus norvegicus
XP_001054618
870
94843
S230
R
R
G
C
A
P
V
S
E
S
A
A
D
G
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517245
456
48674
Chicken
Gallus gallus
XP_416725
892
99815
K249
E
E
K
S
K
L
V
K
E
N
G
D
E
S
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649542
1041
115906
L356
T
S
K
E
D
S
K
L
T
P
T
K
G
A
L
Honey Bee
Apis mellifera
XP_395226
927
105104
E263
E
I
Q
L
S
E
D
E
I
Q
K
I
T
E
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783045
948
103186
E266
L
R
R
K
H
S
S
E
F
L
R
K
I
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
77
N.A.
76.7
63.9
N.A.
34.5
48.7
N.A.
N.A.
N.A.
23.6
23.9
N.A.
26.1
Protein Similarity:
100
N.A.
N.A.
85.5
N.A.
84.4
71
N.A.
43.9
63
N.A.
N.A.
N.A.
38.4
42.8
N.A.
42.7
P-Site Identity:
100
N.A.
N.A.
6.6
N.A.
13.3
60
N.A.
0
20
N.A.
N.A.
N.A.
13.3
6.6
N.A.
13.3
P-Site Similarity:
100
N.A.
N.A.
33.3
N.A.
20
60
N.A.
0
33.3
N.A.
N.A.
N.A.
20
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
23
12
0
0
0
0
23
34
12
12
0
% A
% Cys:
0
0
0
12
12
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
12
0
12
0
0
0
0
12
23
12
45
% D
% Glu:
23
23
12
12
0
12
0
34
34
23
0
0
23
34
12
% E
% Phe:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% F
% Gly:
0
0
23
12
12
0
12
12
0
0
12
12
12
12
12
% G
% His:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
12
0
0
0
0
0
0
12
0
0
12
12
0
0
% I
% Lys:
0
0
23
12
12
0
12
12
0
0
12
23
0
0
0
% K
% Leu:
12
0
0
12
0
12
0
12
0
12
0
0
0
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
12
% N
% Pro:
0
0
0
0
0
12
12
0
0
23
23
0
0
0
0
% P
% Gln:
12
0
12
0
0
0
0
0
0
12
0
0
0
0
0
% Q
% Arg:
34
45
23
0
0
0
0
0
0
0
12
0
0
0
0
% R
% Ser:
0
12
0
23
12
34
23
23
23
12
0
0
0
23
0
% S
% Thr:
12
0
0
0
0
12
0
0
12
0
12
0
12
0
0
% T
% Val:
0
0
0
0
0
0
23
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _