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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HLCS
All Species:
5.45
Human Site:
T146
Identified Species:
15
UniProt:
P50747
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50747
NP_000402.3
726
80760
T146
L
E
S
V
A
D
E
T
S
P
E
R
E
G
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535590
735
81203
S154
L
E
D
V
A
D
D
S
C
P
E
R
E
G
R
Cat
Felis silvestris
Mouse
Mus musculus
Q920N2
722
78498
L145
V
E
G
A
A
G
E
L
C
P
E
R
K
G
K
Rat
Rattus norvegicus
XP_001054618
870
94843
L293
V
E
G
T
A
G
E
L
C
P
E
R
K
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517245
456
48674
Chicken
Gallus gallus
XP_416725
892
99815
N312
C
N
S
K
L
E
E
N
G
D
C
L
T
T
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649542
1041
115906
K419
D
Q
P
T
K
P
R
K
S
F
E
A
V
K
P
Honey Bee
Apis mellifera
XP_395226
927
105104
T326
D
S
K
I
M
V
S
T
S
P
F
K
N
S
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783045
948
103186
G329
I
G
K
L
S
R
S
G
K
H
R
D
E
R
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
77
N.A.
76.7
63.9
N.A.
34.5
48.7
N.A.
N.A.
N.A.
23.6
23.9
N.A.
26.1
Protein Similarity:
100
N.A.
N.A.
85.5
N.A.
84.4
71
N.A.
43.9
63
N.A.
N.A.
N.A.
38.4
42.8
N.A.
42.7
P-Site Identity:
100
N.A.
N.A.
73.3
N.A.
46.6
46.6
N.A.
0
13.3
N.A.
N.A.
N.A.
13.3
20
N.A.
6.6
P-Site Similarity:
100
N.A.
N.A.
86.6
N.A.
66.6
66.6
N.A.
0
20
N.A.
N.A.
N.A.
20
33.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
45
0
0
0
0
0
0
12
0
0
0
% A
% Cys:
12
0
0
0
0
0
0
0
34
0
12
0
0
0
0
% C
% Asp:
23
0
12
0
0
23
12
0
0
12
0
12
0
0
12
% D
% Glu:
0
45
0
0
0
12
45
0
0
0
56
0
34
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
12
12
0
0
0
0
% F
% Gly:
0
12
23
0
0
23
0
12
12
0
0
0
0
45
12
% G
% His:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% H
% Ile:
12
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
23
12
12
0
0
12
12
0
0
12
23
12
23
% K
% Leu:
23
0
0
12
12
0
0
23
0
0
0
12
0
0
0
% L
% Met:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
12
% M
% Asn:
0
12
0
0
0
0
0
12
0
0
0
0
12
0
0
% N
% Pro:
0
0
12
0
0
12
0
0
0
56
0
0
0
0
12
% P
% Gln:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
12
12
0
0
0
12
45
0
12
23
% R
% Ser:
0
12
23
0
12
0
23
12
34
0
0
0
0
12
0
% S
% Thr:
0
0
0
23
0
0
0
23
0
0
0
0
12
12
0
% T
% Val:
23
0
0
23
0
12
0
0
0
0
0
0
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _