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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HLCS
All Species:
12.12
Human Site:
Y167
Identified Species:
33.33
UniProt:
P50747
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50747
NP_000402.3
726
80760
Y167
K
A
P
N
I
L
L
Y
V
G
S
D
S
Q
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535590
735
81203
Y175
K
A
P
N
I
L
F
Y
V
G
S
T
P
Q
E
Cat
Felis silvestris
Mouse
Mus musculus
Q920N2
722
78498
Y166
K
A
P
N
I
L
L
Y
V
G
S
G
S
E
E
Rat
Rattus norvegicus
XP_001054618
870
94843
Y314
K
A
P
N
I
L
L
Y
V
G
S
G
S
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517245
456
48674
Chicken
Gallus gallus
XP_416725
892
99815
L333
A
G
K
P
P
N
I
L
I
Y
V
G
S
G
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649542
1041
115906
P440
S
R
A
A
P
S
R
P
V
L
Q
R
N
K
D
Honey Bee
Apis mellifera
XP_395226
927
105104
P347
L
S
N
K
N
V
K
P
N
V
L
I
Y
A
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783045
948
103186
I350
S
D
S
K
P
P
N
I
L
V
Y
T
G
S
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
77
N.A.
76.7
63.9
N.A.
34.5
48.7
N.A.
N.A.
N.A.
23.6
23.9
N.A.
26.1
Protein Similarity:
100
N.A.
N.A.
85.5
N.A.
84.4
71
N.A.
43.9
63
N.A.
N.A.
N.A.
38.4
42.8
N.A.
42.7
P-Site Identity:
100
N.A.
N.A.
80
N.A.
86.6
86.6
N.A.
0
6.6
N.A.
N.A.
N.A.
6.6
0
N.A.
6.6
P-Site Similarity:
100
N.A.
N.A.
80
N.A.
93.3
93.3
N.A.
0
20
N.A.
N.A.
N.A.
26.6
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
45
12
12
0
0
0
0
0
0
0
0
0
12
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
0
0
0
0
0
0
0
0
0
12
0
0
23
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
23
56
% E
% Phe:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% F
% Gly:
0
12
0
0
0
0
0
0
0
45
0
34
12
12
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
45
0
12
12
12
0
0
12
0
0
0
% I
% Lys:
45
0
12
23
0
0
12
0
0
0
0
0
0
12
0
% K
% Leu:
12
0
0
0
0
45
34
12
12
12
12
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
12
45
12
12
12
0
12
0
0
0
12
0
0
% N
% Pro:
0
0
45
12
34
12
0
23
0
0
0
0
12
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
12
0
0
23
0
% Q
% Arg:
0
12
0
0
0
0
12
0
0
0
0
12
0
0
0
% R
% Ser:
23
12
12
0
0
12
0
0
0
0
45
0
45
12
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
23
0
0
12
% T
% Val:
0
0
0
0
0
12
0
0
56
23
12
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
45
0
12
12
0
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _