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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RASSF2
All Species:
33.94
Human Site:
Y224
Identified Species:
93.33
UniProt:
P50749
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50749
NP_055552.1
326
37790
Y224
S
A
E
E
F
A
L
Y
V
V
H
T
S
G
E
Chimpanzee
Pan troglodytes
XP_001164287
326
37758
Y224
S
A
E
E
F
A
L
Y
V
V
H
T
S
G
E
Rhesus Macaque
Macaca mulatta
XP_001101344
321
36575
Y222
G
P
S
E
F
A
L
Y
I
V
H
E
S
G
E
Dog
Lupus familis
XP_542904
326
37872
Y224
S
A
E
E
F
A
L
Y
V
V
H
T
S
G
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMS9
326
37955
Y224
S
A
E
E
F
A
L
Y
V
V
H
T
S
G
E
Rat
Rattus norvegicus
Q3B7D5
326
38003
Y224
S
A
E
E
F
A
L
Y
V
V
H
T
S
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026055
324
37348
Y222
S
A
E
E
F
A
L
Y
I
V
H
T
S
G
E
Frog
Xenopus laevis
NP_001090216
320
37396
Y218
P
A
S
E
F
S
L
Y
M
V
H
T
S
G
E
Zebra Danio
Brachydanio rerio
NP_001004676
325
37969
Y223
S
P
D
D
F
A
L
Y
L
V
H
A
S
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
57.6
95.7
N.A.
92.6
93.2
N.A.
N.A.
82.2
77.9
64.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
70.2
97.5
N.A.
96.6
96.6
N.A.
N.A.
91.4
86.5
77.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
66.6
100
N.A.
100
100
N.A.
N.A.
93.3
73.3
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
73.3
100
N.A.
100
100
N.A.
N.A.
100
86.6
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
78
0
0
0
89
0
0
0
0
0
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
12
12
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
67
89
0
0
0
0
0
0
0
12
0
0
100
% E
% Phe:
0
0
0
0
100
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
12
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
23
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
100
0
12
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
12
23
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
78
0
23
0
0
12
0
0
0
0
0
0
100
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
78
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
56
100
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _