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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK9
All Species:
34.24
Human Site:
S306
Identified Species:
50.22
UniProt:
P50750
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50750
NP_001252.1
372
42778
S306
D
P
A
Q
R
I
D
S
D
D
A
L
N
H
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001094502
352
40482
S286
D
P
A
Q
R
I
D
S
D
D
A
L
N
H
D
Dog
Lupus familis
XP_548446
534
59045
S468
D
P
A
Q
R
I
D
S
D
D
A
L
N
H
D
Cat
Felis silvestris
Mouse
Mus musculus
NP_570930
372
42743
S306
D
P
A
Q
R
I
D
S
D
D
A
L
N
H
D
Rat
Rattus norvegicus
Q641Z4
372
42743
S306
D
P
A
Q
R
I
D
S
D
D
A
L
N
H
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520593
314
36161
D249
P
A
Q
R
I
D
S
D
D
A
L
N
H
D
F
Chicken
Gallus gallus
Q5ZKN1
372
42784
S306
D
P
A
Q
R
I
D
S
D
D
A
L
N
H
D
Frog
Xenopus laevis
Q4V862
376
43205
S310
D
P
T
Q
R
L
D
S
D
D
A
L
N
N
D
Zebra Danio
Brachydanio rerio
NP_997756
393
45129
S328
D
P
A
Q
R
I
D
S
D
D
A
L
N
H
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477226
404
46768
A338
D
P
K
K
R
I
D
A
D
T
A
L
N
H
D
Honey Bee
Apis mellifera
XP_396015
382
43973
A312
D
P
S
K
R
F
D
A
D
S
A
L
N
H
D
Nematode Worm
Caenorhab. elegans
Q9TVL3
478
53575
S404
D
P
D
K
R
P
T
S
D
E
A
E
D
D
I
Sea Urchin
Strong. purpuratus
XP_798269
410
46418
A335
D
P
K
R
R
M
D
A
A
I
A
L
D
H
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LFT8
505
56711
A316
D
P
A
Q
R
I
S
A
K
D
A
L
D
A
E
Baker's Yeast
Sacchar. cerevisiae
P23293
657
74221
A357
D
P
Y
K
R
L
T
A
M
S
A
K
H
H
P
Red Bread Mold
Neurospora crassa
Q871M9
545
61347
A318
D
W
R
S
R
I
N
A
I
D
A
L
N
H
P
Conservation
Percent
Protein Identity:
100
N.A.
92.4
68.5
N.A.
98.6
98.6
N.A.
77.9
93
89.3
85.5
N.A.
66
72.7
43.3
67.3
Protein Similarity:
100
N.A.
93.5
69.4
N.A.
99.7
99.7
N.A.
80.3
95.4
94.1
89.5
N.A.
75.9
83.2
56.4
75.8
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
6.6
100
80
100
N.A.
73.3
66.6
40
53.3
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
20
100
93.3
100
N.A.
86.6
86.6
60
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
36
25.2
31.7
Protein Similarity:
N.A.
N.A.
N.A.
51
39.4
45.6
P-Site Identity:
N.A.
N.A.
N.A.
60
33.3
53.3
P-Site Similarity:
N.A.
N.A.
N.A.
80
60
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
50
0
0
0
0
38
7
7
94
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
94
0
7
0
0
7
69
7
75
63
0
0
19
13
69
% D
% Glu:
0
0
0
0
0
0
0
0
0
7
0
7
0
0
7
% E
% Phe:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
7
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
13
75
0
% H
% Ile:
0
0
0
0
7
63
0
0
7
7
0
0
0
0
7
% I
% Lys:
0
0
13
25
0
0
0
0
7
0
0
7
0
0
0
% K
% Leu:
0
0
0
0
0
13
0
0
0
0
7
82
0
0
0
% L
% Met:
0
0
0
0
0
7
0
0
7
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
7
0
0
0
0
7
69
7
0
% N
% Pro:
7
88
0
0
0
7
0
0
0
0
0
0
0
0
13
% P
% Gln:
0
0
7
57
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
7
13
94
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
7
7
0
0
13
57
0
13
0
0
0
0
0
% S
% Thr:
0
0
7
0
0
0
13
0
0
7
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _