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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCT8 All Species: 29.09
Human Site: S162 Identified Species: 49.23
UniProt: P50990 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P50990 NP_006576.2 548 59621 S162 R D I D E V S S L L R T S I M
Chimpanzee Pan troglodytes XP_531416 548 59529 S162 R D I D E V S S L L R T S I M
Rhesus Macaque Macaca mulatta XP_001101969 548 59498 S162 R D V D E V S S L L R T S I M
Dog Lupus familis XP_535576 548 59756 T162 R D V D E V S T L L H T S I M
Cat Felis silvestris
Mouse Mus musculus P42932 548 59537 S162 R D V D E V S S L L R T S I M
Rat Rattus norvegicus Q7TPB1 539 58081 T169 T L L N S A T T S L N S K V V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q6EE31 548 59456 S162 R D V D E V A S L L H T S V M
Frog Xenopus laevis NP_001080713 546 59341 S162 R D V D E V A S L L Q T A I M
Zebra Danio Brachydanio rerio NP_957356 546 59283 A162 H D L E E A T A M I R S A V M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610418 546 59415 E162 R N V E K V K E V L R T S I M
Honey Bee Apis mellifera XP_623832 544 59106 M162 K D E K Q I K M G I K T A I M
Nematode Worm Caenorhab. elegans Q9N358 581 63437 Q161 K N I E E V R Q Y I R S A I T
Sea Urchin Strong. purpuratus XP_788106 532 57429 Q148 R N S Q E V T Q A I R T S V M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P47079 568 61644 K161 N D K N E L L K M I K P V I S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 99.4 97.6 N.A. 96.9 28.2 N.A. N.A. 93.2 88.8 85.2 N.A. 61.5 64.4 53.5 66.2
Protein Similarity: 100 99.6 99.6 99.4 N.A. 98.5 51.2 N.A. N.A. 97.2 95 93.2 N.A. 78.4 80.1 70.4 80.2
P-Site Identity: 100 100 93.3 80 N.A. 93.3 6.6 N.A. N.A. 73.3 73.3 26.6 N.A. 53.3 26.6 33.3 46.6
P-Site Similarity: 100 100 100 93.3 N.A. 100 53.3 N.A. N.A. 93.3 100 86.6 N.A. 86.6 66.6 73.3 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 46.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 66.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 15 15 8 8 0 0 0 29 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 72 0 50 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 8 22 79 0 0 8 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % G
% His: 8 0 0 0 0 0 0 0 0 0 15 0 0 0 0 % H
% Ile: 0 0 22 0 0 8 0 0 0 36 0 0 0 72 0 % I
% Lys: 15 0 8 8 8 0 15 8 0 0 15 0 8 0 0 % K
% Leu: 0 8 15 0 0 8 8 0 50 65 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 8 15 0 0 0 0 0 79 % M
% Asn: 8 22 0 15 0 0 0 0 0 0 8 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % P
% Gln: 0 0 0 8 8 0 0 15 0 0 8 0 0 0 0 % Q
% Arg: 65 0 0 0 0 0 8 0 0 0 58 0 0 0 0 % R
% Ser: 0 0 8 0 8 0 36 43 8 0 0 22 58 0 8 % S
% Thr: 8 0 0 0 0 0 22 15 0 0 0 72 0 0 8 % T
% Val: 0 0 43 0 0 72 0 0 8 0 0 0 8 29 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _