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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCT8
All Species:
46.36
Human Site:
Y468
Identified Species:
78.46
UniProt:
P50990
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50990
NP_006576.2
548
59621
Y468
N
E
V
I
S
K
L
Y
A
V
H
Q
E
G
N
Chimpanzee
Pan troglodytes
XP_531416
548
59529
Y468
S
E
V
I
S
K
L
Y
A
V
H
Q
E
G
N
Rhesus Macaque
Macaca mulatta
XP_001101969
548
59498
Y468
N
E
V
I
S
K
L
Y
A
V
H
Q
E
G
N
Dog
Lupus familis
XP_535576
548
59756
Y468
N
E
V
I
S
K
L
Y
A
V
H
Q
E
G
N
Cat
Felis silvestris
Mouse
Mus musculus
P42932
548
59537
Y468
N
E
V
I
S
K
L
Y
S
V
H
Q
E
G
N
Rat
Rattus norvegicus
Q7TPB1
539
58081
R481
I
S
T
V
T
E
L
R
N
R
H
A
Q
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q6EE31
548
59456
Y468
N
E
V
I
S
K
L
Y
A
V
H
Q
E
G
N
Frog
Xenopus laevis
NP_001080713
546
59341
Y468
N
E
V
L
S
K
L
Y
A
M
H
Q
E
G
N
Zebra Danio
Brachydanio rerio
NP_957356
546
59283
Y468
N
E
L
I
S
K
L
Y
A
T
H
H
E
G
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610418
546
59415
Y468
T
E
I
V
N
Q
L
Y
L
A
H
N
N
E
A
Honey Bee
Apis mellifera
XP_623832
544
59106
Y468
S
E
L
L
S
K
L
Y
S
A
H
K
E
G
K
Nematode Worm
Caenorhab. elegans
Q9N358
581
63437
Y501
T
E
T
L
T
K
L
Y
A
E
H
V
A
G
K
Sea Urchin
Strong. purpuratus
XP_788106
532
57429
Y454
T
E
L
L
S
K
L
Y
A
A
H
Q
D
G
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P47079
568
61644
Y479
N
E
V
L
P
N
L
Y
A
A
H
N
V
T
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
99.4
97.6
N.A.
96.9
28.2
N.A.
N.A.
93.2
88.8
85.2
N.A.
61.5
64.4
53.5
66.2
Protein Similarity:
100
99.6
99.6
99.4
N.A.
98.5
51.2
N.A.
N.A.
97.2
95
93.2
N.A.
78.4
80.1
70.4
80.2
P-Site Identity:
100
93.3
100
100
N.A.
93.3
20
N.A.
N.A.
100
86.6
80
N.A.
26.6
53.3
46.6
60
P-Site Similarity:
100
100
100
100
N.A.
100
46.6
N.A.
N.A.
100
100
86.6
N.A.
53.3
86.6
60
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
66.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
72
29
0
8
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% D
% Glu:
0
93
0
0
0
8
0
0
0
8
0
0
65
8
15
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
86
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
100
8
0
0
0
% H
% Ile:
8
0
8
50
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
79
0
0
0
0
0
8
0
0
15
% K
% Leu:
0
0
22
36
0
0
100
0
8
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
58
0
0
0
8
8
0
0
8
0
0
15
8
0
58
% N
% Pro:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
0
58
8
0
8
% Q
% Arg:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% R
% Ser:
15
8
0
0
72
0
0
0
15
0
0
0
0
0
0
% S
% Thr:
22
0
15
0
15
0
0
0
0
8
0
0
0
8
0
% T
% Val:
0
0
58
15
0
0
0
0
0
43
0
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
93
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _