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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCT4
All Species:
43.64
Human Site:
S177
Identified Species:
64
UniProt:
P50991
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50991
NP_006421.2
539
57924
S177
S
L
N
S
K
V
V
S
Q
Y
S
S
L
L
S
Chimpanzee
Pan troglodytes
XP_001152144
652
69933
S290
S
L
N
S
K
V
V
S
Q
Y
S
S
L
L
S
Rhesus Macaque
Macaca mulatta
XP_001114200
500
54012
I169
T
S
V
D
L
R
D
I
K
I
V
K
K
L
G
Dog
Lupus familis
XP_539390
539
58020
S177
S
L
N
S
K
V
V
S
Q
Y
S
S
L
L
S
Cat
Felis silvestris
Mouse
Mus musculus
P80315
539
58048
S177
S
L
N
S
K
V
V
S
Q
Y
S
S
L
L
S
Rat
Rattus norvegicus
Q7TPB1
539
58081
S177
S
L
N
S
K
V
V
S
Q
Y
S
S
L
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512619
518
55936
A169
L
S
P
M
S
V
D
A
V
M
K
V
I
D
P
Chicken
Gallus gallus
NP_996761
536
57718
C174
S
L
N
S
K
V
V
C
Q
Y
S
S
L
L
S
Frog
Xenopus laevis
NP_001083498
541
57867
S179
S
L
N
S
K
V
V
S
Q
Y
S
S
L
L
A
Zebra Danio
Brachydanio rerio
NP_956877
533
56955
S171
S
L
C
S
K
V
V
S
Q
N
S
S
L
L
A
Tiger Blowfish
Takifugu rubipres
P53451
536
57697
S174
S
L
C
S
K
V
V
S
Q
Y
S
S
L
L
A
Fruit Fly
Dros. melanogaster
NP_609579
533
57098
S170
S
L
N
S
K
V
V
S
Q
Q
S
S
L
L
A
Honey Bee
Apis mellifera
XP_623672
534
57361
F171
S
L
N
S
K
V
V
F
Q
Q
S
S
L
L
A
Nematode Worm
Caenorhab. elegans
P47208
540
58373
S176
S
L
N
S
K
V
V
S
Q
H
S
W
L
L
A
Sea Urchin
Strong. purpuratus
XP_784913
531
57115
S169
S
L
N
S
K
V
V
S
Q
Y
S
G
L
L
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39078
528
57585
D176
F
L
A
P
L
A
V
D
S
V
L
K
I
S
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.6
92.3
98.1
N.A.
96.6
96.8
N.A.
89.8
91.6
89.4
86.4
87
68
69.7
63.3
76
Protein Similarity:
100
82.6
92.7
98.5
N.A.
97.9
97.9
N.A.
93.3
96.4
95.7
94.4
94.6
84.2
86
80
88.1
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
6.6
93.3
93.3
80
86.6
86.6
80
80
86.6
P-Site Similarity:
100
100
20
100
N.A.
100
100
N.A.
20
93.3
100
86.6
93.3
93.3
86.6
93.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
58.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
80.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
7
0
7
0
0
0
0
0
0
44
% A
% Cys:
0
0
13
0
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
0
0
13
7
0
0
0
0
0
7
7
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
7
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
7
0
7
0
0
13
0
0
% I
% Lys:
0
0
0
0
82
0
0
0
7
0
7
13
7
0
0
% K
% Leu:
7
88
0
0
13
0
0
0
0
0
7
0
82
88
0
% L
% Met:
0
0
0
7
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
0
69
0
0
0
0
0
0
7
0
0
0
0
0
% N
% Pro:
0
0
7
7
0
0
0
0
0
0
0
0
0
0
7
% P
% Gln:
0
0
0
0
0
0
0
0
82
13
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% R
% Ser:
82
13
0
82
7
0
0
69
7
0
82
69
0
7
38
% S
% Thr:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
7
0
0
88
88
0
7
7
7
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
57
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _