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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCT4 All Species: 41.21
Human Site: S202 Identified Species: 60.44
UniProt: P50991 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P50991 NP_006421.2 539 57924 S202 I D P A T A T S V D L R D I K
Chimpanzee Pan troglodytes XP_001152144 652 69933 S315 I D P A T A T S V D L R D I K
Rhesus Macaque Macaca mulatta XP_001114200 500 54012 V194 G L V L T Q K V S N S G I T R
Dog Lupus familis XP_539390 539 58020 S202 I D P A T A T S V D L R D I K
Cat Felis silvestris
Mouse Mus musculus P80315 539 58048 S202 I D P A T A T S V D L R D I K
Rat Rattus norvegicus Q7TPB1 539 58081 S202 I D P A T A T S V D L R D I K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512619 518 55936 G194 I K I V K K L G G T I D D C E
Chicken Gallus gallus NP_996761 536 57718 S199 I D P S T A S S V D L R D I K
Frog Xenopus laevis NP_001083498 541 57867 S204 I D P Q T A N S V D L R D I K
Zebra Danio Brachydanio rerio NP_956877 533 56955 S196 I D P A T A T S V D L R D I N
Tiger Blowfish Takifugu rubipres P53451 536 57697 S199 I D P A T A T S V D L H D I K
Fruit Fly Dros. melanogaster NP_609579 533 57098 S195 T D P G K E T S V D L K N I K
Honey Bee Apis mellifera XP_623672 534 57361 T196 T E E G K E S T V D L N N I K
Nematode Worm Caenorhab. elegans P47208 540 58373 N201 I N S E N D S N V N L K M I K
Sea Urchin Strong. purpuratus XP_784913 531 57115 N194 I D S S T A T N V D L T D I K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P39078 528 57585 G201 I R L V K K V G G T I D D T E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 82.6 92.3 98.1 N.A. 96.6 96.8 N.A. 89.8 91.6 89.4 86.4 87 68 69.7 63.3 76
Protein Similarity: 100 82.6 92.7 98.5 N.A. 97.9 97.9 N.A. 93.3 96.4 95.7 94.4 94.6 84.2 86 80 88.1
P-Site Identity: 100 100 6.6 100 N.A. 100 100 N.A. 13.3 86.6 86.6 93.3 93.3 60 33.3 33.3 73.3
P-Site Similarity: 100 100 20 100 N.A. 100 100 N.A. 26.6 100 86.6 93.3 93.3 73.3 60 66.6 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 58.4 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 80.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 44 0 63 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % C
% Asp: 0 69 0 0 0 7 0 0 0 75 0 13 75 0 0 % D
% Glu: 0 7 7 7 0 13 0 0 0 0 0 0 0 0 13 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 7 0 0 13 0 0 0 13 13 0 0 7 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % H
% Ile: 82 0 7 0 0 0 0 0 0 0 13 0 7 82 0 % I
% Lys: 0 7 0 0 25 13 7 0 0 0 0 13 0 0 75 % K
% Leu: 0 7 7 7 0 0 7 0 0 0 82 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % M
% Asn: 0 7 0 0 7 0 7 13 0 13 0 7 13 0 7 % N
% Pro: 0 0 63 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 7 0 7 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 7 0 0 0 0 0 0 0 0 0 50 0 0 7 % R
% Ser: 0 0 13 13 0 0 19 63 7 0 7 0 0 0 0 % S
% Thr: 13 0 0 0 69 0 57 7 0 13 0 7 0 13 0 % T
% Val: 0 0 7 13 0 0 7 7 82 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _