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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCT4
All Species:
41.21
Human Site:
T149
Identified Species:
60.44
UniProt:
P50991
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50991
NP_006421.2
539
57924
T149
E
K
G
I
E
I
L
T
D
M
S
R
P
V
E
Chimpanzee
Pan troglodytes
XP_001152144
652
69933
T262
E
K
G
I
E
I
L
T
D
M
S
R
P
V
E
Rhesus Macaque
Macaca mulatta
XP_001114200
500
54012
S141
S
K
V
V
S
Q
Y
S
S
L
L
S
P
M
S
Dog
Lupus familis
XP_539390
539
58020
T149
E
K
G
I
E
I
L
T
D
M
S
R
P
V
E
Cat
Felis silvestris
Mouse
Mus musculus
P80315
539
58048
T149
E
K
G
L
E
I
L
T
D
M
S
R
P
V
Q
Rat
Rattus norvegicus
Q7TPB1
539
58081
T149
E
K
G
L
E
I
L
T
D
M
S
R
P
V
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512619
518
55936
T141
V
E
L
S
D
R
E
T
L
L
N
S
A
T
T
Chicken
Gallus gallus
NP_996761
536
57718
T146
E
K
G
I
E
V
L
T
N
M
A
Q
P
V
E
Frog
Xenopus laevis
NP_001083498
541
57867
T151
E
K
A
I
E
V
L
T
S
M
S
Q
S
V
E
Zebra Danio
Brachydanio rerio
NP_956877
533
56955
T143
D
K
G
V
E
V
L
T
S
I
S
T
P
L
L
Tiger Blowfish
Takifugu rubipres
P53451
536
57697
T146
D
K
G
V
E
V
L
T
A
M
S
Q
P
V
Q
Fruit Fly
Dros. melanogaster
NP_609579
533
57098
K142
N
K
A
V
E
I
L
K
Q
M
S
T
P
I
E
Honey Bee
Apis mellifera
XP_623672
534
57361
T143
A
K
A
V
E
I
L
T
N
M
S
I
P
V
D
Nematode Worm
Caenorhab. elegans
P47208
540
58373
D148
A
E
A
E
K
I
L
D
E
M
S
S
P
V
D
Sea Urchin
Strong. purpuratus
XP_784913
531
57115
A141
D
K
A
C
E
I
L
A
D
M
S
V
S
V
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39078
528
57585
E148
K
V
S
L
S
D
R
E
Q
L
V
R
A
A
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.6
92.3
98.1
N.A.
96.6
96.8
N.A.
89.8
91.6
89.4
86.4
87
68
69.7
63.3
76
Protein Similarity:
100
82.6
92.7
98.5
N.A.
97.9
97.9
N.A.
93.3
96.4
95.7
94.4
94.6
84.2
86
80
88.1
P-Site Identity:
100
100
13.3
100
N.A.
86.6
86.6
N.A.
6.6
73.3
66.6
46.6
60
53.3
60
40
53.3
P-Site Similarity:
100
100
40
100
N.A.
100
100
N.A.
33.3
100
80
80
93.3
66.6
80
66.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
58.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
80.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
32
0
0
0
0
7
7
0
7
0
13
7
0
% A
% Cys:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
19
0
0
0
7
7
0
7
38
0
0
0
0
0
13
% D
% Glu:
44
13
0
7
75
0
7
7
7
0
0
0
0
0
38
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
50
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
32
0
57
0
0
0
7
0
7
0
7
0
% I
% Lys:
7
82
0
0
7
0
0
7
0
0
0
0
0
0
7
% K
% Leu:
0
0
7
19
0
0
82
0
7
19
7
0
0
7
7
% L
% Met:
0
0
0
0
0
0
0
0
0
75
0
0
0
7
0
% M
% Asn:
7
0
0
0
0
0
0
0
13
0
7
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
75
0
0
% P
% Gln:
0
0
0
0
0
7
0
0
13
0
0
19
0
0
19
% Q
% Arg:
0
0
0
0
0
7
7
0
0
0
0
38
0
0
0
% R
% Ser:
7
0
7
7
13
0
0
7
19
0
75
19
13
0
13
% S
% Thr:
0
0
0
0
0
0
0
69
0
0
0
13
0
7
7
% T
% Val:
7
7
7
32
0
25
0
0
0
0
7
7
0
69
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _