KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCT4
All Species:
37.27
Human Site:
T258
Identified Species:
54.67
UniProt:
P50991
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50991
NP_006421.2
539
57924
T258
F
C
L
S
A
P
K
T
D
M
D
N
Q
I
V
Chimpanzee
Pan troglodytes
XP_001152144
652
69933
T371
F
C
L
S
A
P
K
T
D
M
D
N
Q
I
V
Rhesus Macaque
Macaca mulatta
XP_001114200
500
54012
Q250
Y
I
L
N
L
V
K
Q
I
K
K
T
G
C
N
Dog
Lupus familis
XP_539390
539
58020
T258
F
C
L
S
A
P
K
T
D
M
D
N
Q
I
V
Cat
Felis silvestris
Mouse
Mus musculus
P80315
539
58048
T258
F
C
L
S
A
P
K
T
D
M
D
N
Q
I
V
Rat
Rattus norvegicus
Q7TPB1
539
58081
T258
F
C
L
S
A
P
K
T
D
M
D
N
Q
I
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512619
518
55936
Q250
I
V
V
S
D
Y
A
Q
M
D
R
V
L
R
E
Chicken
Gallus gallus
NP_996761
536
57718
T255
F
C
L
S
A
P
K
T
D
M
D
N
Q
I
V
Frog
Xenopus laevis
NP_001083498
541
57867
T260
F
C
L
S
A
P
K
T
D
M
D
N
Q
I
V
Zebra Danio
Brachydanio rerio
NP_956877
533
56955
T252
F
C
L
S
P
P
K
T
D
M
D
N
Q
I
V
Tiger Blowfish
Takifugu rubipres
P53451
536
57697
T255
F
C
L
S
P
P
K
T
D
M
D
N
Q
I
V
Fruit Fly
Dros. melanogaster
NP_609579
533
57098
K251
Q
F
C
I
S
A
P
K
T
D
M
D
H
N
V
Honey Bee
Apis mellifera
XP_623672
534
57361
K252
Q
F
C
I
S
P
P
K
T
D
M
D
H
N
V
Nematode Worm
Caenorhab. elegans
P47208
540
58373
K257
Q
F
Q
I
S
P
P
K
T
D
M
E
N
Q
V
Sea Urchin
Strong. purpuratus
XP_784913
531
57115
K250
Q
F
C
L
S
A
P
K
T
D
M
D
N
Q
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39078
528
57585
Y257
N
N
I
I
V
N
D
Y
R
Q
M
D
K
I
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.6
92.3
98.1
N.A.
96.6
96.8
N.A.
89.8
91.6
89.4
86.4
87
68
69.7
63.3
76
Protein Similarity:
100
82.6
92.7
98.5
N.A.
97.9
97.9
N.A.
93.3
96.4
95.7
94.4
94.6
84.2
86
80
88.1
P-Site Identity:
100
100
13.3
100
N.A.
100
100
N.A.
6.6
100
100
93.3
93.3
6.6
13.3
13.3
6.6
P-Site Similarity:
100
100
26.6
100
N.A.
100
100
N.A.
13.3
100
100
93.3
93.3
20
26.6
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
58.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
80.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
44
13
7
0
0
0
0
0
0
0
0
% A
% Cys:
0
57
19
0
0
0
0
0
0
0
0
0
0
7
0
% C
% Asp:
0
0
0
0
7
0
7
0
57
32
57
25
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
7
% E
% Phe:
57
25
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% H
% Ile:
7
7
7
25
0
0
0
0
7
0
0
0
0
63
0
% I
% Lys:
0
0
0
0
0
0
63
25
0
7
7
0
7
0
0
% K
% Leu:
0
0
63
7
7
0
0
0
0
0
0
0
7
0
7
% L
% Met:
0
0
0
0
0
0
0
0
7
57
32
0
0
0
0
% M
% Asn:
7
7
0
7
0
7
0
0
0
0
0
57
13
13
7
% N
% Pro:
0
0
0
0
13
69
25
0
0
0
0
0
0
0
0
% P
% Gln:
25
0
7
0
0
0
0
13
0
7
0
0
57
13
0
% Q
% Arg:
0
0
0
0
0
0
0
0
7
0
7
0
0
7
0
% R
% Ser:
0
0
0
63
25
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
57
25
0
0
7
0
0
0
% T
% Val:
0
7
7
0
7
7
0
0
0
0
0
7
0
0
82
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
7
0
7
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _