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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCT4 All Species: 56.06
Human Site: T387 Identified Species: 82.22
UniProt: P50991 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P50991 NP_006421.2 539 57924 T387 A S P G K T V T I V V R G S N
Chimpanzee Pan troglodytes XP_001152144 652 69933 T500 A S P G K T V T I V V R G S N
Rhesus Macaque Macaca mulatta XP_001114200 500 54012 S365 V I E E A E R S I H D A L C V
Dog Lupus familis XP_539390 539 58020 T387 T S P G K T V T I V V R G S N
Cat Felis silvestris
Mouse Mus musculus P80315 539 58048 T387 T S P G K T V T I V V R G S N
Rat Rattus norvegicus Q7TPB1 539 58081 T387 T S P G K T V T I V V R G S N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512619 518 55936 T366 A S P G K T V T I V V R G S N
Chicken Gallus gallus NP_996761 536 57718 T384 T N P G K T V T I V V R G S N
Frog Xenopus laevis NP_001083498 541 57867 T389 A N P G K T V T I V V R G S N
Zebra Danio Brachydanio rerio NP_956877 533 56955 S381 A S P G K T V S I V V R G S N
Tiger Blowfish Takifugu rubipres P53451 536 57697 S384 A S P G K T V S I V V R G S N
Fruit Fly Dros. melanogaster NP_609579 533 57098 S380 Q N M G R T V S I I C R G S N
Honey Bee Apis mellifera XP_623672 534 57361 T381 Q N P G P T V T V L V R G S N
Nematode Worm Caenorhab. elegans P47208 540 58373 S387 Q N P G H A V S I L L R G S N
Sea Urchin Strong. purpuratus XP_784913 531 57115 T379 A T P G K T M T V L V R G S N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P39078 528 57585 V375 N N N A R P T V S V V I R G A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 82.6 92.3 98.1 N.A. 96.6 96.8 N.A. 89.8 91.6 89.4 86.4 87 68 69.7 63.3 76
Protein Similarity: 100 82.6 92.7 98.5 N.A. 97.9 97.9 N.A. 93.3 96.4 95.7 94.4 94.6 84.2 86 80 88.1
P-Site Identity: 100 100 6.6 93.3 N.A. 93.3 93.3 N.A. 100 86.6 93.3 93.3 93.3 53.3 66.6 53.3 73.3
P-Site Similarity: 100 100 13.3 93.3 N.A. 93.3 93.3 N.A. 100 93.3 100 100 100 80 86.6 80 100
Percent
Protein Identity: N.A. N.A. N.A. N.A. 58.4 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 80.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 44 0 0 7 7 7 0 0 0 0 0 7 0 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 7 0 0 7 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % D
% Glu: 0 0 7 7 0 7 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 88 0 0 0 0 0 0 0 0 88 7 0 % G
% His: 0 0 0 0 7 0 0 0 0 7 0 0 0 0 0 % H
% Ile: 0 7 0 0 0 0 0 0 82 7 0 7 0 0 0 % I
% Lys: 0 0 0 0 69 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 19 7 0 7 0 0 % L
% Met: 0 0 7 0 0 0 7 0 0 0 0 0 0 0 0 % M
% Asn: 7 38 7 0 0 0 0 0 0 0 0 0 0 0 88 % N
% Pro: 0 0 82 0 7 7 0 0 0 0 0 0 0 0 0 % P
% Gln: 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 13 0 7 0 0 0 0 88 7 0 0 % R
% Ser: 0 50 0 0 0 0 0 32 7 0 0 0 0 88 0 % S
% Thr: 25 7 0 0 0 82 7 63 0 0 0 0 0 0 0 % T
% Val: 7 0 0 0 0 0 82 7 13 69 82 0 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _