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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCT4
All Species:
36.06
Human Site:
Y269
Identified Species:
52.89
UniProt:
P50991
Number Species:
15
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50991
NP_006421.2
539
57924
Y269
N
Q
I
V
V
S
D
Y
A
Q
M
D
R
V
L
Chimpanzee
Pan troglodytes
XP_001152144
652
69933
Y382
N
Q
I
V
V
S
D
Y
A
Q
M
D
R
V
L
Rhesus Macaque
Macaca mulatta
XP_001114200
500
54012
I261
T
G
C
N
V
L
L
I
Q
K
S
I
L
R
D
Dog
Lupus familis
XP_539390
539
58020
Y269
N
Q
I
V
V
S
D
Y
V
Q
M
D
R
V
L
Cat
Felis silvestris
Mouse
Mus musculus
P80315
539
58048
Y269
N
Q
I
V
V
S
D
Y
A
Q
M
D
R
V
L
Rat
Rattus norvegicus
Q7TPB1
539
58081
Y269
N
Q
I
V
V
S
D
Y
A
Q
M
D
R
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512619
518
55936
Y261
V
L
R
E
E
R
A
Y
I
L
N
L
V
K
Q
Chicken
Gallus gallus
NP_996761
536
57718
Y266
N
Q
I
V
V
S
D
Y
A
Q
M
D
R
V
L
Frog
Xenopus laevis
NP_001083498
541
57867
Y271
N
Q
I
V
V
S
D
Y
A
Q
M
D
R
V
L
Zebra Danio
Brachydanio rerio
NP_956877
533
56955
Y263
N
Q
I
V
V
S
D
Y
A
Q
M
D
R
V
L
Tiger Blowfish
Takifugu rubipres
P53451
536
57697
Y266
N
Q
I
V
V
S
D
Y
T
Q
M
D
R
V
L
Fruit Fly
Dros. melanogaster
NP_609579
533
57098
D262
D
H
N
V
I
V
S
D
Y
A
A
M
D
R
V
Honey Bee
Apis mellifera
XP_623672
534
57361
D263
D
H
N
V
I
V
S
D
Y
A
A
M
D
R
V
Nematode Worm
Caenorhab. elegans
P47208
540
58373
D268
E
N
Q
V
I
I
T
D
Y
A
Q
M
D
R
A
Sea Urchin
Strong. purpuratus
XP_784913
531
57115
D261
D
N
Q
V
V
V
S
D
Y
T
Q
M
D
R
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39078
528
57585
R268
D
K
I
L
K
E
E
R
A
Y
L
L
N
I
C
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.6
92.3
98.1
N.A.
96.6
96.8
N.A.
89.8
91.6
89.4
86.4
87
68
69.7
63.3
76
Protein Similarity:
100
82.6
92.7
98.5
N.A.
97.9
97.9
N.A.
93.3
96.4
95.7
94.4
94.6
84.2
86
80
88.1
P-Site Identity:
100
100
6.6
93.3
N.A.
100
100
N.A.
6.6
100
100
100
93.3
6.6
6.6
6.6
13.3
P-Site Similarity:
100
100
13.3
93.3
N.A.
100
100
N.A.
6.6
100
100
100
93.3
26.6
26.6
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
58.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
80.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
7
0
50
19
13
0
0
0
7
% A
% Cys:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
7
% C
% Asp:
25
0
0
0
0
0
57
25
0
0
0
57
25
0
7
% D
% Glu:
7
0
0
7
7
7
7
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
63
0
19
7
0
7
7
0
0
7
0
7
0
% I
% Lys:
0
7
0
0
7
0
0
0
0
7
0
0
0
7
0
% K
% Leu:
0
7
0
7
0
7
7
0
0
7
7
13
7
0
57
% L
% Met:
0
0
0
0
0
0
0
0
0
0
57
25
0
0
0
% M
% Asn:
57
13
13
7
0
0
0
0
0
0
7
0
7
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
57
13
0
0
0
0
0
7
57
13
0
0
0
7
% Q
% Arg:
0
0
7
0
0
7
0
7
0
0
0
0
57
32
0
% R
% Ser:
0
0
0
0
0
57
19
0
0
0
7
0
0
0
0
% S
% Thr:
7
0
0
0
0
0
7
0
7
7
0
0
0
0
0
% T
% Val:
7
0
0
82
69
19
0
0
7
0
0
0
7
57
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
63
25
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _