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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCT4
All Species:
59.09
Human Site:
Y449
Identified Species:
86.67
UniProt:
P50991
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50991
NP_006421.2
539
57924
Y449
T
L
S
G
M
E
S
Y
C
V
R
A
F
A
D
Chimpanzee
Pan troglodytes
XP_001152144
652
69933
Y562
T
L
S
G
M
E
S
Y
C
V
R
A
F
A
D
Rhesus Macaque
Macaca mulatta
XP_001114200
500
54012
Y410
T
L
S
G
M
E
S
Y
C
V
R
A
F
A
D
Dog
Lupus familis
XP_539390
539
58020
Y449
T
L
S
G
M
E
S
Y
C
V
R
A
F
A
D
Cat
Felis silvestris
Mouse
Mus musculus
P80315
539
58048
Y449
T
L
S
G
M
E
S
Y
C
V
R
A
F
A
D
Rat
Rattus norvegicus
Q7TPB1
539
58081
Y449
T
L
S
G
M
E
S
Y
C
V
R
A
F
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512619
518
55936
Y428
T
L
S
G
M
E
S
Y
C
V
R
A
F
A
D
Chicken
Gallus gallus
NP_996761
536
57718
Y446
T
L
R
G
M
D
S
Y
C
V
R
A
Y
G
D
Frog
Xenopus laevis
NP_001083498
541
57867
Y451
A
L
S
G
M
E
S
Y
C
I
R
A
F
A
D
Zebra Danio
Brachydanio rerio
NP_956877
533
56955
Y443
S
L
G
G
M
E
A
Y
C
V
R
A
Y
A
D
Tiger Blowfish
Takifugu rubipres
P53451
536
57697
Y446
T
L
G
G
M
E
A
Y
C
V
R
A
Y
S
D
Fruit Fly
Dros. melanogaster
NP_609579
533
57098
Y442
T
V
E
G
V
D
A
Y
C
F
R
A
F
A
D
Honey Bee
Apis mellifera
XP_623672
534
57361
Y443
T
L
T
G
V
D
A
Y
C
I
N
A
F
A
N
Nematode Worm
Caenorhab. elegans
P47208
540
58373
Y449
T
Q
H
G
A
T
Q
Y
C
W
R
A
F
A
D
Sea Urchin
Strong. purpuratus
XP_784913
531
57115
Y441
S
L
S
G
M
E
A
Y
C
F
R
A
Y
A
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39078
528
57585
F438
S
M
E
G
V
Q
A
F
I
W
Q
E
F
A
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.6
92.3
98.1
N.A.
96.6
96.8
N.A.
89.8
91.6
89.4
86.4
87
68
69.7
63.3
76
Protein Similarity:
100
82.6
92.7
98.5
N.A.
97.9
97.9
N.A.
93.3
96.4
95.7
94.4
94.6
84.2
86
80
88.1
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
73.3
86.6
73.3
73.3
60
53.3
60
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
86.6
93.3
93.3
93.3
86.6
93.3
60
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
58.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
80.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
7
0
38
0
0
0
0
94
0
88
0
% A
% Cys:
0
0
0
0
0
0
0
0
94
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
19
0
0
0
0
0
0
0
0
82
% D
% Glu:
0
0
13
0
0
69
0
0
0
0
0
7
0
0
7
% E
% Phe:
0
0
0
0
0
0
0
7
0
13
0
0
75
0
0
% F
% Gly:
0
0
13
100
0
0
0
0
0
0
0
0
0
7
0
% G
% His:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
7
13
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
82
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
7
0
0
75
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
7
0
0
0
7
7
0
0
0
7
0
0
0
0
% Q
% Arg:
0
0
7
0
0
0
0
0
0
0
88
0
0
0
0
% R
% Ser:
19
0
57
0
0
0
57
0
0
0
0
0
0
7
7
% S
% Thr:
75
0
7
0
0
7
0
0
0
0
0
0
0
0
0
% T
% Val:
0
7
0
0
19
0
0
0
0
63
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
94
0
0
0
0
25
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _