KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP1A2
All Species:
31.82
Human Site:
T614
Identified Species:
77.78
UniProt:
P50993
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50993
NP_000693.1
1020
112265
T614
G
I
K
V
I
M
V
T
G
D
H
P
I
T
A
Chimpanzee
Pan troglodytes
XP_513921
999
109933
C603
V
P
D
A
V
G
K
C
R
S
A
G
I
K
V
Rhesus Macaque
Macaca mulatta
XP_001115318
1078
118405
T672
G
I
K
V
I
M
V
T
G
D
H
P
I
T
A
Dog
Lupus familis
XP_545753
981
107334
G584
T
E
K
L
C
F
V
G
L
M
S
M
I
D
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8VDN2
1023
112964
T617
G
I
K
V
I
M
V
T
G
D
H
P
I
T
A
Rat
Rattus norvegicus
P06686
1020
112199
T614
G
I
K
V
I
M
V
T
G
D
H
P
I
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P24797
1017
112033
T611
G
I
K
V
I
M
V
T
G
D
H
P
I
T
A
Frog
Xenopus laevis
Q92123
1025
113066
T619
G
I
K
V
I
M
V
T
G
D
H
P
I
T
A
Zebra Danio
Brachydanio rerio
NP_571759
1023
112505
T617
G
I
K
V
I
M
V
T
G
D
H
P
I
T
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13607
1041
115586
T635
G
I
K
V
I
M
V
T
G
D
H
P
I
T
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.7
94.3
95.5
N.A.
86.2
99.1
N.A.
N.A.
93.6
86.9
85.1
N.A.
74.5
N.A.
N.A.
N.A.
Protein Similarity:
100
97.8
94.6
96
N.A.
93.2
99.8
N.A.
N.A.
97.5
94.2
92.8
N.A.
84.9
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
20
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
100
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
100
26.6
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
100
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
0
0
10
0
0
0
80
% A
% Cys:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
0
80
0
0
0
10
0
% D
% Glu:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
80
0
0
0
0
10
0
10
80
0
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
80
0
0
0
0
% H
% Ile:
0
80
0
0
80
0
0
0
0
0
0
0
100
0
0
% I
% Lys:
0
0
90
0
0
0
10
0
0
0
0
0
0
10
0
% K
% Leu:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
80
0
0
0
10
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
0
0
0
0
0
0
0
0
80
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% S
% Thr:
10
0
0
0
0
0
0
80
0
0
0
0
0
80
0
% T
% Val:
10
0
0
80
10
0
90
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _