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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAPOLA All Species: 4.55
Human Site: S509 Identified Species: 9.09
UniProt: P51003 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51003 NP_116021.2 745 82843 S509 L Q K K K K H S T E G V K L T
Chimpanzee Pan troglodytes XP_515496 714 80108 L476 Q A N N I N M L K E G M K I E
Rhesus Macaque Macaca mulatta XP_001101831 825 90125 S457 L Q K K K K H S T E G V K L T
Dog Lupus familis XP_537551 812 90509 Q576 L L P N H V L Q K K K K H S T
Cat Felis silvestris
Mouse Mus musculus Q61183 739 82291 Q503 L L P S H V L Q K R K K H S T
Rat Rattus norvegicus NP_001101526 739 82082 Q503 L L P S H V L Q K R K K H S T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511509 736 82218 Q500 L L P N H V L Q K K K K H S M
Chicken Gallus gallus XP_421352 737 82879 Q502 L L P N H V L Q K K K K H S T
Frog Xenopus laevis P51004 715 80169 Q479 R K Q L H Q L Q P S H V S P K
Zebra Danio Brachydanio rerio NP_991321 723 80246 K488 K I T A M H V K R K Q L H Q L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393202 615 69546 L381 K Y K H Y I V L L A R S L T A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P29468 568 64534 I334 E F V R G V Q I T N D I F S N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 59.8 78.4 89.7 N.A. 95.5 95 N.A. 95.5 89.9 80.1 70.3 N.A. N.A. 49.7 N.A. N.A.
Protein Similarity: 100 72.6 80.7 90.1 N.A. 97.4 96.7 N.A. 96.9 93.8 86.3 80 N.A. N.A. 62.2 N.A. N.A.
P-Site Identity: 100 20 100 13.3 N.A. 13.3 13.3 N.A. 6.6 13.3 6.6 0 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 100 33.3 100 20 N.A. 13.3 13.3 N.A. 13.3 20 26.6 13.3 N.A. N.A. 6.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 33.1 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 49.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 9 0 0 0 0 0 9 0 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % D
% Glu: 9 0 0 0 0 0 0 0 0 25 0 0 0 0 9 % E
% Phe: 0 9 0 0 0 0 0 0 0 0 0 0 9 0 0 % F
% Gly: 0 0 0 0 9 0 0 0 0 0 25 0 0 0 0 % G
% His: 0 0 0 9 50 9 17 0 0 0 9 0 50 0 0 % H
% Ile: 0 9 0 0 9 9 0 9 0 0 0 9 0 9 0 % I
% Lys: 17 9 25 17 17 17 0 9 50 34 42 42 25 0 9 % K
% Leu: 59 42 0 9 0 0 50 17 9 0 0 9 9 17 9 % L
% Met: 0 0 0 0 9 0 9 0 0 0 0 9 0 0 9 % M
% Asn: 0 0 9 34 0 9 0 0 0 9 0 0 0 0 9 % N
% Pro: 0 0 42 0 0 0 0 0 9 0 0 0 0 9 0 % P
% Gln: 9 17 9 0 0 9 9 50 0 0 9 0 0 9 0 % Q
% Arg: 9 0 0 9 0 0 0 0 9 17 9 0 0 0 0 % R
% Ser: 0 0 0 17 0 0 0 17 0 9 0 9 9 50 0 % S
% Thr: 0 0 9 0 0 0 0 0 25 0 0 0 0 9 50 % T
% Val: 0 0 9 0 0 50 17 0 0 0 0 25 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 0 9 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _