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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAPOLA All Species: 7.27
Human Site: S549 Identified Species: 14.55
UniProt: P51003 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.36
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51003 NP_116021.2 745 82843 S549 T K T S P L N S S G S S Q G R
Chimpanzee Pan troglodytes XP_515496 714 80108 S516 L S D V N R S S G G L Q S K R
Rhesus Macaque Macaca mulatta XP_001101831 825 90125 S497 T K T S P L N S S G S S Q G R
Dog Lupus familis XP_537551 812 90509 K616 P S P T S A M K T S P L N S S
Cat Felis silvestris
Mouse Mus musculus Q61183 739 82291 K543 P S P T S A M K T S P L N S S
Rat Rattus norvegicus NP_001101526 739 82082 K543 P S P T S A M K T S P L N S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511509 736 82218 K540 P S P T S A M K T S P L N S S
Chicken Gallus gallus XP_421352 737 82879 K542 P S P T S A M K T S P L N S S
Frog Xenopus laevis P51004 715 80169 S519 D N S M S V P S P T N A T R T
Zebra Danio Brachydanio rerio NP_991321 723 80246 D528 L D L S L D S D N S M S V P S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393202 615 69546 N421 H I T L A H V N P E A F P P L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P29468 568 64534 Q374 Y T R G S D E Q H L K W S G L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 59.8 78.4 89.7 N.A. 95.5 95 N.A. 95.5 89.9 80.1 70.3 N.A. N.A. 49.7 N.A. N.A.
Protein Similarity: 100 72.6 80.7 90.1 N.A. 97.4 96.7 N.A. 96.9 93.8 86.3 80 N.A. N.A. 62.2 N.A. N.A.
P-Site Identity: 100 20 100 0 N.A. 0 0 N.A. 0 0 6.6 13.3 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 100 26.6 100 13.3 N.A. 13.3 13.3 N.A. 13.3 13.3 33.3 26.6 N.A. N.A. 20 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 33.1 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 49.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 9 42 0 0 0 0 9 9 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 9 9 0 0 17 0 9 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 9 0 0 9 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % F
% Gly: 0 0 0 9 0 0 0 0 9 25 0 0 0 25 0 % G
% His: 9 0 0 0 0 9 0 0 9 0 0 0 0 0 0 % H
% Ile: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 17 0 0 0 0 0 42 0 0 9 0 0 9 0 % K
% Leu: 17 0 9 9 9 17 0 0 0 9 9 42 0 0 17 % L
% Met: 0 0 0 9 0 0 42 0 0 0 9 0 0 0 0 % M
% Asn: 0 9 0 0 9 0 17 9 9 0 9 0 42 0 0 % N
% Pro: 42 0 42 0 17 0 9 0 17 0 42 0 9 17 0 % P
% Gln: 0 0 0 0 0 0 0 9 0 0 0 9 17 0 0 % Q
% Arg: 0 0 9 0 0 9 0 0 0 0 0 0 0 9 25 % R
% Ser: 0 50 9 25 59 0 17 34 17 50 17 25 17 42 50 % S
% Thr: 17 9 25 42 0 0 0 0 42 9 0 0 9 0 9 % T
% Val: 0 0 0 9 0 9 9 0 0 0 0 0 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % W
% Tyr: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _