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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FXR1
All Species:
31.82
Human Site:
Y477
Identified Species:
70
UniProt:
P51114
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51114
NP_001013456.1
621
69721
Y477
K
D
P
D
S
N
P
Y
S
L
L
D
N
T
E
Chimpanzee
Pan troglodytes
XP_001169031
650
72774
Y506
K
D
P
D
S
N
P
Y
S
L
L
D
N
T
E
Rhesus Macaque
Macaca mulatta
XP_001098757
721
80175
Y577
K
D
P
D
S
N
P
Y
S
L
L
D
N
T
E
Dog
Lupus familis
XP_856150
621
69730
Y477
K
D
P
D
S
N
P
Y
S
L
L
D
N
T
E
Cat
Felis silvestris
Mouse
Mus musculus
Q61584
677
76203
Y506
K
D
P
D
S
N
P
Y
S
L
L
D
N
T
E
Rat
Rattus norvegicus
Q5XI81
568
63929
G427
R
G
P
N
Y
T
S
G
Y
G
T
N
S
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506480
842
93552
Y701
K
D
P
D
S
N
P
Y
S
L
L
D
N
T
E
Chicken
Gallus gallus
NP_001012619
650
72793
Y506
K
D
P
D
S
N
P
Y
S
L
L
D
N
T
E
Frog
Xenopus laevis
P51115
676
76194
Y506
K
D
P
D
S
N
P
Y
S
L
L
D
N
T
E
Zebra Danio
Brachydanio rerio
NP_958458
624
69826
R479
R
G
R
G
R
G
S
R
G
R
G
S
G
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9NFU0
684
76057
H520
R
D
Y
Q
H
H
N
H
T
T
E
E
V
R
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.5
85.8
99.6
N.A.
89.9
68.2
N.A.
70.5
88.3
80.7
74.3
N.A.
36.1
N.A.
N.A.
N.A.
Protein Similarity:
100
95.5
86.1
100
N.A.
90.9
73.2
N.A.
72
91.6
86.5
84.9
N.A.
54.3
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
100
100
100
0
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
33.3
N.A.
100
100
100
6.6
N.A.
46.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
82
0
73
0
0
0
0
0
0
0
73
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
10
10
0
10
82
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
19
0
10
0
10
0
10
10
10
10
0
10
0
0
% G
% His:
0
0
0
0
10
10
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
73
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
73
73
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
73
10
0
0
0
0
10
73
0
0
% N
% Pro:
0
0
82
0
0
0
73
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
28
0
10
0
10
0
0
10
0
10
0
0
0
10
0
% R
% Ser:
0
0
0
0
73
0
19
0
73
0
0
10
10
0
10
% S
% Thr:
0
0
0
0
0
10
0
0
10
10
10
0
0
73
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
10
0
0
73
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _