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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FXR2
All Species:
18.18
Human Site:
Y409
Identified Species:
40
UniProt:
P51116
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51116
NP_004851.1
673
74223
Y409
G
G
S
D
K
A
G
Y
S
T
D
E
S
S
S
Chimpanzee
Pan troglodytes
XP_001171332
673
74237
Y409
G
G
S
D
K
A
G
Y
S
T
D
E
S
S
S
Rhesus Macaque
Macaca mulatta
XP_001118084
862
93486
Y598
G
G
S
D
K
A
G
Y
S
T
D
E
S
S
S
Dog
Lupus familis
XP_546596
890
97000
Y627
G
G
S
D
K
A
G
Y
T
T
D
E
S
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVR4
673
73724
Y411
G
G
S
D
K
A
G
Y
T
T
D
E
S
S
S
Rat
Rattus norvegicus
Q5XI81
568
63929
V308
G
K
V
I
Q
E
I
V
D
K
S
G
V
V
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506480
842
93552
H578
V
Q
V
L
L
E
Y
H
I
A
Y
L
K
E
V
Chicken
Gallus gallus
NP_001012619
650
72793
P390
R
P
S
S
A
R
V
P
E
K
E
K
G
Y
T
Frog
Xenopus laevis
P51115
676
76194
K394
S
R
G
T
E
K
E
K
G
Y
A
T
D
E
S
Zebra Danio
Brachydanio rerio
XP_002662865
676
74848
E412
S
G
S
G
V
A
G
E
R
E
R
G
Y
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9NFU0
684
76057
R401
T
Q
S
F
P
V
T
R
R
S
E
R
G
Y
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
77.7
74.1
N.A.
95.8
58.5
N.A.
46.5
60.9
62.4
68.1
N.A.
34.9
N.A.
N.A.
N.A.
Protein Similarity:
100
100
77.7
75
N.A.
97
69
N.A.
56.5
73.1
76.7
77.8
N.A.
54.2
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
6.6
N.A.
0
6.6
6.6
26.6
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
6.6
26.6
13.3
33.3
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
55
0
0
0
10
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
46
0
0
0
0
10
0
46
0
10
0
0
% D
% Glu:
0
0
0
0
10
19
10
10
10
10
19
46
0
19
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
55
55
10
10
0
0
55
0
10
0
0
19
19
0
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
10
0
10
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
46
10
0
10
0
19
0
10
10
0
0
% K
% Leu:
0
0
0
10
10
0
0
0
0
0
0
10
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
0
10
0
0
10
0
0
0
0
0
0
0
% P
% Gln:
0
19
0
0
10
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
10
0
0
0
10
0
10
19
0
10
10
0
0
10
% R
% Ser:
19
0
73
10
0
0
0
0
28
10
10
0
46
46
64
% S
% Thr:
10
0
0
10
0
0
10
0
19
46
0
10
0
0
19
% T
% Val:
10
0
19
0
10
10
10
10
0
0
0
0
10
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
46
0
10
10
0
10
19
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _