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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GZMM
All Species:
3.33
Human Site:
S160
Identified Species:
8.15
UniProt:
P51124
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51124
NP_005308.1
257
27545
S160
T
H
Q
G
G
R
L
S
R
V
L
R
E
L
D
Chimpanzee
Pan troglodytes
XP_512221
253
27033
V156
D
V
A
G
W
G
I
V
N
H
A
G
R
R
P
Rhesus Macaque
Macaca mulatta
XP_001105086
97
10566
Dog
Lupus familis
XP_542217
536
56133
L418
S
V
S
D
F
E
D
L
P
P
G
L
M
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q14B24
284
30322
P177
F
V
S
D
F
E
E
P
P
P
G
L
M
E
V
Rat
Rattus norvegicus
Q03238
258
28321
A157
T
H
Q
R
G
Q
L
A
K
S
L
Q
E
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517361
237
25958
K143
F
T
N
N
L
G
K
K
P
D
K
L
Q
Q
V
Chicken
Gallus gallus
NP_989788
260
28466
S158
S
K
R
G
N
K
M
S
D
T
L
R
E
V
N
Frog
Xenopus laevis
Q63ZK0
263
29212
P164
M
K
S
T
G
K
K
P
D
T
L
Q
E
L
W
Zebra Danio
Brachydanio rerio
XP_001343605
284
31651
N188
G
W
G
D
L
W
N
N
G
P
V
S
D
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42.4
33.4
20.1
N.A.
40.1
67.4
N.A.
36.5
34.2
34.5
35.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
59.5
34.2
28.5
N.A.
54.2
80.2
N.A.
55.6
53.4
52
49.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
0
0
N.A.
0
60
N.A.
0
33.3
26.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
0
6.6
N.A.
0
86.6
N.A.
6.6
73.3
40
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
10
0
0
10
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
30
0
0
10
0
20
10
0
0
10
0
20
% D
% Glu:
0
0
0
0
0
20
10
0
0
0
0
0
40
20
0
% E
% Phe:
20
0
0
0
20
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
10
30
30
20
0
0
10
0
20
10
0
0
0
% G
% His:
0
20
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
0
20
0
0
0
20
20
10
10
0
10
0
0
0
0
% K
% Leu:
0
0
0
0
20
0
20
10
0
0
40
30
0
30
10
% L
% Met:
10
0
0
0
0
0
10
0
0
0
0
0
20
0
0
% M
% Asn:
0
0
10
10
10
0
10
10
10
0
0
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
0
20
30
30
0
0
0
0
10
% P
% Gln:
0
0
20
0
0
10
0
0
0
0
0
20
10
10
0
% Q
% Arg:
0
0
10
10
0
10
0
0
10
0
0
20
10
20
0
% R
% Ser:
20
0
30
0
0
0
0
20
0
10
0
10
0
0
0
% S
% Thr:
20
10
0
10
0
0
0
0
0
20
0
0
0
0
0
% T
% Val:
0
30
0
0
0
0
0
10
0
10
10
0
0
10
20
% V
% Trp:
0
10
0
0
10
10
0
0
0
0
0
0
0
0
10
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _