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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RAB5C
All Species:
46.67
Human Site:
S124
Identified Species:
78.97
UniProt:
P51148
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51148
NP_004574.2
216
23483
S124
K
E
L
Q
R
Q
A
S
P
N
I
V
I
A
L
Chimpanzee
Pan troglodytes
XP_516319
216
23697
S123
K
E
L
Q
R
Q
A
S
P
N
I
V
I
A
L
Rhesus Macaque
Macaca mulatta
XP_001086669
215
23622
S123
K
E
L
Q
R
Q
A
S
P
N
T
V
I
A
L
Dog
Lupus familis
XP_856128
222
24457
S123
K
E
L
Q
R
Q
A
S
P
S
I
V
I
A
L
Cat
Felis silvestris
Mouse
Mus musculus
P35278
216
23394
S124
K
E
L
Q
R
Q
A
S
P
N
I
V
I
A
L
Rat
Rattus norvegicus
Q6GQP4
194
21350
P108
K
E
L
K
E
H
G
P
E
N
I
V
M
A
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508982
215
23635
S123
K
E
L
Q
R
Q
A
S
P
N
I
V
I
A
L
Chicken
Gallus gallus
Q98932
216
23535
S124
K
E
L
Q
R
Q
A
S
P
N
I
V
I
A
L
Frog
Xenopus laevis
NP_001080714
215
23616
S124
K
E
L
Q
R
Q
A
S
P
N
I
V
I
A
L
Zebra Danio
Brachydanio rerio
NP_958893
216
23476
S124
K
E
L
Q
R
Q
A
S
P
N
I
V
I
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783878
216
23603
S122
K
E
L
Q
R
Q
A
S
P
N
I
V
I
A
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q05737
203
22457
S111
N
E
I
D
R
Y
A
S
D
N
V
N
K
L
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P31582
200
21635
N113
Q
E
L
Q
A
Q
G
N
P
N
M
V
M
A
L
Baker's Yeast
Sacchar. cerevisiae
P36017
210
23062
S110
K
E
L
H
E
Q
A
S
K
D
I
I
I
A
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87
84.7
81.9
N.A.
98.6
44.9
N.A.
88.4
94.4
93.9
85.6
N.A.
N.A.
N.A.
N.A.
84.2
Protein Similarity:
100
91.6
89.8
88.7
N.A.
99
61.1
N.A.
92.1
96.7
96.3
92.5
N.A.
N.A.
N.A.
N.A.
88.8
P-Site Identity:
100
100
93.3
93.3
N.A.
100
46.6
N.A.
100
100
100
100
N.A.
N.A.
N.A.
N.A.
100
P-Site Similarity:
100
100
93.3
100
N.A.
100
66.6
N.A.
100
100
100
100
N.A.
N.A.
N.A.
N.A.
100
Percent
Protein Identity:
N.A.
39.8
N.A.
58.8
53.7
N.A.
Protein Similarity:
N.A.
56.4
N.A.
68.9
67.5
N.A.
P-Site Identity:
N.A.
40
N.A.
60
66.6
N.A.
P-Site Similarity:
N.A.
53.3
N.A.
86.6
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
86
0
0
0
0
0
0
93
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
8
8
0
0
0
0
0
% D
% Glu:
0
100
0
0
15
0
0
0
8
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
15
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
79
8
79
0
8
% I
% Lys:
86
0
0
8
0
0
0
0
8
0
0
0
8
0
0
% K
% Leu:
0
0
93
0
0
0
0
0
0
0
0
0
0
8
93
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
15
0
0
% M
% Asn:
8
0
0
0
0
0
0
8
0
86
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
79
0
0
0
0
0
0
% P
% Gln:
8
0
0
79
0
86
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
79
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
86
0
8
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
8
86
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _