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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RAB5C
All Species:
13.64
Human Site:
S140
Identified Species:
23.08
UniProt:
P51148
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51148
NP_004574.2
216
23483
S140
G
N
K
A
D
L
A
S
K
R
A
V
E
F
Q
Chimpanzee
Pan troglodytes
XP_516319
216
23697
N139
G
N
K
A
D
L
A
N
K
R
A
V
D
F
Q
Rhesus Macaque
Macaca mulatta
XP_001086669
215
23622
N139
G
N
K
A
N
L
A
N
K
R
A
V
N
F
Q
Dog
Lupus familis
XP_856128
222
24457
N139
G
N
K
A
D
L
A
N
K
R
M
V
E
Y
E
Cat
Felis silvestris
Mouse
Mus musculus
P35278
216
23394
S140
G
N
K
A
D
L
A
S
K
R
A
V
E
F
Q
Rat
Rattus norvegicus
Q6GQP4
194
21350
D124
G
N
K
C
D
L
S
D
I
R
E
V
P
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508982
215
23635
N139
G
N
K
A
D
L
A
N
K
R
A
V
D
F
Q
Chicken
Gallus gallus
Q98932
216
23535
T140
G
N
K
A
D
L
A
T
K
R
A
V
D
F
Q
Frog
Xenopus laevis
NP_001080714
215
23616
S140
G
N
K
A
D
L
S
S
K
R
A
V
D
F
Q
Zebra Danio
Brachydanio rerio
NP_958893
216
23476
N140
G
N
K
A
D
L
A
N
K
R
A
V
D
F
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783878
216
23603
N138
G
N
K
A
D
L
A
N
K
R
M
V
E
F
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q05737
203
22457
A127
G
N
K
S
D
L
T
A
N
K
V
V
A
T
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P31582
200
21635
D129
G
N
K
A
D
L
L
D
A
R
K
V
S
A
E
Baker's Yeast
Sacchar. cerevisiae
P36017
210
23062
G129
I
D
M
L
Q
E
G
G
E
R
K
V
A
R
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87
84.7
81.9
N.A.
98.6
44.9
N.A.
88.4
94.4
93.9
85.6
N.A.
N.A.
N.A.
N.A.
84.2
Protein Similarity:
100
91.6
89.8
88.7
N.A.
99
61.1
N.A.
92.1
96.7
96.3
92.5
N.A.
N.A.
N.A.
N.A.
88.8
P-Site Identity:
100
86.6
80
73.3
N.A.
100
46.6
N.A.
86.6
86.6
86.6
86.6
N.A.
N.A.
N.A.
N.A.
80
P-Site Similarity:
100
100
93.3
93.3
N.A.
100
60
N.A.
100
100
100
100
N.A.
N.A.
N.A.
N.A.
93.3
Percent
Protein Identity:
N.A.
39.8
N.A.
58.8
53.7
N.A.
Protein Similarity:
N.A.
56.4
N.A.
68.9
67.5
N.A.
P-Site Identity:
N.A.
40
N.A.
53.3
13.3
N.A.
P-Site Similarity:
N.A.
66.6
N.A.
60
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
79
0
0
65
8
8
0
58
0
15
8
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
86
0
0
15
0
0
0
0
36
0
0
% D
% Glu:
0
0
0
0
0
8
0
0
8
0
8
0
29
0
36
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
65
0
% F
% Gly:
93
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
0
0
93
0
0
0
0
0
72
8
15
0
0
0
8
% K
% Leu:
0
0
0
8
0
93
8
0
0
0
0
0
0
8
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
15
0
0
0
0
% M
% Asn:
0
93
0
0
8
0
0
43
8
0
0
0
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
58
% Q
% Arg:
0
0
0
0
0
0
0
0
0
93
0
0
0
8
0
% R
% Ser:
0
0
0
8
0
0
15
22
0
0
0
0
8
0
0
% S
% Thr:
0
0
0
0
0
0
8
8
0
0
0
0
0
8
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
8
100
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _