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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RAB5C
All Species:
24.85
Human Site:
S209
Identified Species:
42.05
UniProt:
P51148
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51148
NP_004574.2
216
23483
S209
L
Q
E
N
N
P
A
S
R
S
Q
C
C
S
N
Chimpanzee
Pan troglodytes
XP_516319
216
23697
T209
L
T
E
P
T
Q
P
T
R
N
Q
C
C
S
N
Rhesus Macaque
Macaca mulatta
XP_001086669
215
23622
T208
L
T
E
P
T
R
P
T
R
S
Q
C
C
S
N
Dog
Lupus familis
XP_856128
222
24457
N215
L
H
E
Q
S
Q
Q
N
K
S
Q
C
C
S
N
Cat
Felis silvestris
Mouse
Mus musculus
P35278
216
23394
S209
L
Q
E
S
N
P
A
S
R
S
Q
C
C
S
N
Rat
Rattus norvegicus
Q6GQP4
194
21350
L187
I
K
L
G
N
Q
S
L
Q
A
G
R
R
C
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508982
215
23635
S208
L
T
E
H
T
L
P
S
R
S
Q
C
C
S
N
Chicken
Gallus gallus
Q98932
216
23535
S209
L
Q
E
S
S
Q
P
S
R
S
Q
C
C
S
N
Frog
Xenopus laevis
NP_001080714
215
23616
Zebra Danio
Brachydanio rerio
NP_958893
216
23476
T209
L
T
E
T
A
Q
P
T
K
A
P
C
C
S
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783878
216
23603
S209
L
T
E
S
N
Q
Q
S
S
G
G
C
C
K
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q05737
203
22457
Q196
I
R
G
Q
P
V
N
Q
K
T
S
C
C
S
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P31582
200
21635
A191
V
L
P
N
G
P
G
A
T
A
V
S
S
S
C
Baker's Yeast
Sacchar. cerevisiae
P36017
210
23062
S203
N
A
A
N
D
G
T
S
A
N
S
A
C
S
C
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87
84.7
81.9
N.A.
98.6
44.9
N.A.
88.4
94.4
93.9
85.6
N.A.
N.A.
N.A.
N.A.
84.2
Protein Similarity:
100
91.6
89.8
88.7
N.A.
99
61.1
N.A.
92.1
96.7
96.3
92.5
N.A.
N.A.
N.A.
N.A.
88.8
P-Site Identity:
100
53.3
60
53.3
N.A.
93.3
6.6
N.A.
66.6
73.3
0
40
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
66.6
66.6
73.3
N.A.
100
40
N.A.
73.3
86.6
0
60
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
39.8
N.A.
58.8
53.7
N.A.
Protein Similarity:
N.A.
56.4
N.A.
68.9
67.5
N.A.
P-Site Identity:
N.A.
20
N.A.
20
26.6
N.A.
P-Site Similarity:
N.A.
53.3
N.A.
40
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
8
0
15
8
8
22
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
72
79
8
22
% C
% Asp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
65
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
8
8
8
8
0
0
8
15
0
0
0
0
% G
% His:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
0
0
0
0
0
22
0
0
0
0
8
0
% K
% Leu:
65
8
8
0
0
8
0
8
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
22
29
0
8
8
0
15
0
0
0
0
65
% N
% Pro:
0
0
8
15
8
22
36
0
0
0
8
0
0
0
0
% P
% Gln:
0
22
0
15
0
43
15
8
8
0
50
0
0
0
0
% Q
% Arg:
0
8
0
0
0
8
0
0
43
0
0
8
8
0
0
% R
% Ser:
0
0
0
22
15
0
8
43
8
43
15
8
8
79
8
% S
% Thr:
0
36
0
8
22
0
8
22
8
8
0
0
0
0
0
% T
% Val:
8
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _