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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RAB7A
All Species:
36.36
Human Site:
Y183
Identified Species:
61.54
UniProt:
P51149
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51149
NP_004628.4
207
23490
Y183
Q
E
T
E
V
E
L
Y
N
E
F
P
E
P
I
Chimpanzee
Pan troglodytes
XP_526302
287
31542
Y263
Q
E
T
E
V
E
L
Y
N
E
F
P
E
P
I
Rhesus Macaque
Macaca mulatta
XP_001095709
296
32366
Y272
Q
E
T
E
V
E
L
Y
N
E
F
P
E
P
I
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8BHH2
201
22686
H181
A
V
E
E
Q
L
E
H
C
M
L
G
H
T
I
Rat
Rattus norvegicus
P09527
207
23485
Y183
Q
E
T
E
V
E
L
Y
N
E
F
P
E
P
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414359
207
23529
Y183
Q
E
T
E
V
E
L
Y
N
E
F
P
E
P
I
Frog
Xenopus laevis
NP_001087006
207
23528
Y183
Q
E
T
E
V
E
L
Y
N
E
F
P
E
P
I
Zebra Danio
Brachydanio rerio
NP_957222
207
23534
Y183
Q
E
T
E
V
E
L
Y
N
E
F
P
E
P
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524472
207
23313
I183
L
E
A
E
A
E
V
I
N
D
F
P
D
Q
I
Honey Bee
Apis mellifera
XP_001120025
207
23218
Y183
Q
E
S
E
V
E
L
Y
N
E
F
P
D
Q
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001116983
205
23050
Y183
Q
E
P
D
D
S
T
Y
Q
D
F
P
S
Q
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04157
203
22926
A178
C
I
T
K
L
A
L
A
N
E
R
D
Q
D
I
Baker's Yeast
Sacchar. cerevisiae
P32939
208
23024
A186
Q
N
Q
A
D
T
E
A
F
E
D
D
Y
N
D
Red Bread Mold
Neurospora crassa
Q9C2L8
205
23110
S185
Q
E
E
S
E
E
F
S
G
D
F
Q
D
P
I
Conservation
Percent
Protein Identity:
100
69.3
67.5
N.A.
N.A.
52.6
99.5
N.A.
N.A.
99
96.6
97.5
N.A.
76.3
82.6
N.A.
82.6
Protein Similarity:
100
71.7
68.2
N.A.
N.A.
68.1
100
N.A.
N.A.
99
98.5
98.5
N.A.
87.9
91.7
N.A.
91.3
P-Site Identity:
100
100
100
N.A.
N.A.
13.3
100
N.A.
N.A.
100
100
100
N.A.
46.6
80
N.A.
40
P-Site Similarity:
100
100
100
N.A.
N.A.
20
100
N.A.
N.A.
100
100
100
N.A.
66.6
93.3
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
62.3
62.5
74.4
Protein Similarity:
N.A.
N.A.
N.A.
77.7
75.9
83.5
P-Site Identity:
N.A.
N.A.
N.A.
33.3
13.3
40
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
13.3
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
8
8
8
0
15
0
0
0
0
0
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
15
0
0
0
0
22
8
15
22
8
8
% D
% Glu:
0
79
15
72
8
72
15
0
0
72
0
0
50
0
0
% E
% Phe:
0
0
0
0
0
0
8
0
8
0
79
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% H
% Ile:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
93
% I
% Lys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
0
0
8
8
65
0
0
0
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
72
0
0
0
0
8
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
0
72
0
58
0
% P
% Gln:
79
0
8
0
8
0
0
0
8
0
0
8
8
22
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
0
0
8
8
0
8
0
8
0
0
0
0
8
0
0
% S
% Thr:
0
0
58
0
0
8
8
0
0
0
0
0
0
8
0
% T
% Val:
0
8
0
0
58
0
8
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
65
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _