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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDE6C
All Species:
15.45
Human Site:
S40
Identified Species:
26.15
UniProt:
P51160
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51160
NP_006195.3
858
99147
S40
L
G
E
I
F
K
N
S
Q
V
P
V
Q
S
S
Chimpanzee
Pan troglodytes
XP_001148438
858
99157
S40
L
G
E
I
F
K
N
S
Q
V
P
V
Q
S
S
Rhesus Macaque
Macaca mulatta
XP_001092604
858
99206
S40
L
G
E
I
F
K
N
S
Q
V
P
V
Q
S
S
Dog
Lupus familis
XP_543934
846
97567
P38
A
P
G
P
S
G
T
P
Q
P
T
E
E
W
A
Cat
Felis silvestris
Mouse
Mus musculus
Q91ZQ1
861
98767
S40
L
G
V
I
F
K
N
S
H
A
G
V
Q
T
G
Rat
Rattus norvegicus
Q8VID6
935
104553
L51
S
G
Q
G
A
S
D
L
R
P
A
L
A
G
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506083
861
99448
P39
V
I
S
E
L
L
G
P
K
E
T
S
V
D
F
Chicken
Gallus gallus
P52731
862
99990
S40
L
G
S
I
F
Q
V
S
P
G
D
V
K
E
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_957165
852
98238
E37
V
I
A
A
A
F
E
E
K
L
D
I
K
D
P
Tiger Blowfish
Takifugu rubipres
Q1KKS3
903
102001
G45
W
L
K
N
H
Q
A
G
K
S
E
A
E
P
K
Fruit Fly
Dros. melanogaster
Q9VFI9
1131
125621
R193
L
Q
E
F
I
E
N
R
K
P
H
K
R
P
S
Honey Bee
Apis mellifera
XP_394107
1016
115998
S165
A
K
R
S
K
S
P
S
R
M
Y
T
S
L
V
Nematode Worm
Caenorhab. elegans
P91119
710
81117
Sea Urchin
Strong. purpuratus
NP_001029121
949
108476
R97
L
R
N
L
L
S
P
R
R
R
K
S
T
L
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.7
88.5
N.A.
86.5
23.8
N.A.
62.9
82.7
N.A.
69.4
24.2
23.7
25.3
22.9
33.3
Protein Similarity:
100
99.8
99.6
94
N.A.
93.9
45
N.A.
80
91.6
N.A.
82.5
43.1
40.3
44.1
41.3
53.6
P-Site Identity:
100
100
100
6.6
N.A.
60
6.6
N.A.
0
40
N.A.
0
0
26.6
6.6
0
6.6
P-Site Similarity:
100
100
100
20
N.A.
66.6
40
N.A.
13.3
53.3
N.A.
33.3
26.6
46.6
20
0
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
8
8
15
0
8
0
0
8
8
8
8
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
0
15
0
0
15
0
% D
% Glu:
0
0
29
8
0
8
8
8
0
8
8
8
15
8
0
% E
% Phe:
0
0
0
8
36
8
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
43
8
8
0
8
8
8
0
8
8
0
0
8
15
% G
% His:
0
0
0
0
8
0
0
0
8
0
8
0
0
0
0
% H
% Ile:
0
15
0
36
8
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
0
8
8
0
8
29
0
0
29
0
8
8
15
0
15
% K
% Leu:
50
8
0
8
15
8
0
8
0
8
0
8
0
15
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
8
8
0
0
36
0
0
0
0
0
0
0
0
% N
% Pro:
0
8
0
8
0
0
15
15
8
22
22
0
0
15
8
% P
% Gln:
0
8
8
0
0
15
0
0
29
0
0
0
29
0
0
% Q
% Arg:
0
8
8
0
0
0
0
15
22
8
0
0
8
0
0
% R
% Ser:
8
0
15
8
8
22
0
43
0
8
0
15
8
22
29
% S
% Thr:
0
0
0
0
0
0
8
0
0
0
15
8
8
8
0
% T
% Val:
15
0
8
0
0
0
8
0
0
22
0
36
8
0
8
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _