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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDE6C
All Species:
10.61
Human Site:
S47
Identified Species:
17.95
UniProt:
P51160
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51160
NP_006195.3
858
99147
S47
S
Q
V
P
V
Q
S
S
M
S
F
S
E
L
T
Chimpanzee
Pan troglodytes
XP_001148438
858
99157
S47
S
Q
V
P
V
Q
S
S
M
S
F
S
E
L
T
Rhesus Macaque
Macaca mulatta
XP_001092604
858
99206
S47
S
Q
V
P
V
Q
S
S
M
S
F
S
E
L
T
Dog
Lupus familis
XP_543934
846
97567
A45
P
Q
P
T
E
E
W
A
V
C
T
E
L
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q91ZQ1
861
98767
G47
S
H
A
G
V
Q
T
G
L
S
L
P
E
M
T
Rat
Rattus norvegicus
Q8VID6
935
104553
A58
L
R
P
A
L
A
G
A
S
S
L
A
Q
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506083
861
99448
F46
P
K
E
T
S
V
D
F
S
H
Y
H
T
L
T
Chicken
Gallus gallus
P52731
862
99990
G47
S
P
G
D
V
K
E
G
V
S
F
K
D
M
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_957165
852
98238
P44
E
K
L
D
I
K
D
P
A
S
F
K
D
V
T
Tiger Blowfish
Takifugu rubipres
Q1KKS3
903
102001
K52
G
K
S
E
A
E
P
K
E
E
K
S
S
V
C
Fruit Fly
Dros. melanogaster
Q9VFI9
1131
125621
S200
R
K
P
H
K
R
P
S
V
T
S
D
L
F
Q
Honey Bee
Apis mellifera
XP_394107
1016
115998
V172
S
R
M
Y
T
S
L
V
G
R
R
E
E
L
N
Nematode Worm
Caenorhab. elegans
P91119
710
81117
Sea Urchin
Strong. purpuratus
NP_001029121
949
108476
K104
R
R
R
K
S
T
L
K
R
N
K
S
A
L
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.7
88.5
N.A.
86.5
23.8
N.A.
62.9
82.7
N.A.
69.4
24.2
23.7
25.3
22.9
33.3
Protein Similarity:
100
99.8
99.6
94
N.A.
93.9
45
N.A.
80
91.6
N.A.
82.5
43.1
40.3
44.1
41.3
53.6
P-Site Identity:
100
100
100
13.3
N.A.
40
6.6
N.A.
13.3
26.6
N.A.
20
6.6
6.6
20
0
13.3
P-Site Similarity:
100
100
100
33.3
N.A.
60
46.6
N.A.
26.6
60
N.A.
60
26.6
33.3
33.3
0
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
8
8
0
15
8
0
0
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% C
% Asp:
0
0
0
15
0
0
15
0
0
0
0
8
15
0
0
% D
% Glu:
8
0
8
8
8
15
8
0
8
8
0
15
36
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
36
0
0
8
0
% F
% Gly:
8
0
8
8
0
0
8
15
8
0
0
0
0
0
0
% G
% His:
0
8
0
8
0
0
0
0
0
8
0
8
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
29
0
8
8
15
0
15
0
0
15
15
0
0
0
% K
% Leu:
8
0
8
0
8
0
15
0
8
0
15
0
15
50
8
% L
% Met:
0
0
8
0
0
0
0
0
22
0
0
0
0
15
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% N
% Pro:
15
8
22
22
0
0
15
8
0
0
0
8
0
0
0
% P
% Gln:
0
29
0
0
0
29
0
0
0
0
0
0
8
0
8
% Q
% Arg:
15
22
8
0
0
8
0
0
8
8
8
0
0
0
8
% R
% Ser:
43
0
8
0
15
8
22
29
15
50
8
36
8
8
15
% S
% Thr:
0
0
0
15
8
8
8
0
0
8
8
0
8
0
43
% T
% Val:
0
0
22
0
36
8
0
8
22
0
0
0
0
15
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _