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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDE6C
All Species:
35.76
Human Site:
S97
Identified Species:
60.51
UniProt:
P51160
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51160
NP_006195.3
858
99147
S97
L
L
Q
A
D
R
C
S
M
F
L
C
R
S
R
Chimpanzee
Pan troglodytes
XP_001148438
858
99157
S97
L
L
Q
A
D
R
C
S
M
F
L
C
R
S
R
Rhesus Macaque
Macaca mulatta
XP_001092604
858
99206
S97
L
L
Q
A
D
R
C
S
M
F
L
C
R
S
R
Dog
Lupus familis
XP_543934
846
97567
T92
T
C
R
A
R
N
G
T
P
E
V
A
S
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q91ZQ1
861
98767
S97
L
L
Q
A
D
C
C
S
M
F
S
C
R
A
R
Rat
Rattus norvegicus
Q8VID6
935
104553
S128
L
R
K
S
F
A
R
S
K
A
I
H
V
N
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506083
861
99448
S95
L
L
H
A
D
R
M
S
L
F
M
Y
R
T
R
Chicken
Gallus gallus
P52731
862
99990
S97
L
L
A
R
D
R
C
S
M
F
I
C
R
S
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_957165
852
98238
S93
L
V
N
A
D
R
C
S
Y
F
I
A
R
A
R
Tiger Blowfish
Takifugu rubipres
Q1KKS3
903
102001
R113
P
L
T
S
M
R
R
R
A
L
L
R
K
A
S
Fruit Fly
Dros. melanogaster
Q9VFI9
1131
125621
S282
L
T
H
A
D
R
G
S
L
F
L
A
K
G
T
Honey Bee
Apis mellifera
XP_394107
1016
115998
S221
L
T
H
A
D
R
G
S
L
F
L
A
K
G
P
Nematode Worm
Caenorhab. elegans
P91119
710
81117
N47
M
K
Y
K
N
V
K
N
G
T
S
G
G
T
G
Sea Urchin
Strong. purpuratus
NP_001029121
949
108476
S153
L
T
N
G
D
R
C
S
L
F
L
A
R
G
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.7
88.5
N.A.
86.5
23.8
N.A.
62.9
82.7
N.A.
69.4
24.2
23.7
25.3
22.9
33.3
Protein Similarity:
100
99.8
99.6
94
N.A.
93.9
45
N.A.
80
91.6
N.A.
82.5
43.1
40.3
44.1
41.3
53.6
P-Site Identity:
100
100
100
6.6
N.A.
80
20
N.A.
60
80
N.A.
60
20
46.6
46.6
0
53.3
P-Site Similarity:
100
100
100
26.6
N.A.
86.6
46.6
N.A.
80
86.6
N.A.
80
40
60
60
26.6
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
65
0
8
0
0
8
8
0
36
0
22
0
% A
% Cys:
0
8
0
0
0
8
50
0
0
0
0
36
0
0
0
% C
% Asp:
0
0
0
0
72
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
72
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
22
0
8
0
0
8
8
22
8
% G
% His:
0
0
22
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
22
0
0
0
0
% I
% Lys:
0
8
8
8
0
0
8
0
8
0
0
0
22
0
0
% K
% Leu:
79
50
0
0
0
0
0
0
29
8
50
0
0
0
8
% L
% Met:
8
0
0
0
8
0
8
0
36
0
8
0
0
0
0
% M
% Asn:
0
0
15
0
8
8
0
8
0
0
0
0
0
8
0
% N
% Pro:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% P
% Gln:
0
0
29
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
8
8
8
72
15
8
0
0
0
8
58
8
58
% R
% Ser:
0
0
0
15
0
0
0
79
0
0
15
0
8
29
8
% S
% Thr:
8
22
8
0
0
0
0
8
0
8
0
0
0
15
15
% T
% Val:
0
8
0
0
0
8
0
0
0
0
8
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
8
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _