KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDE6C
All Species:
33.64
Human Site:
T285
Identified Species:
56.92
UniProt:
P51160
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51160
NP_006195.3
858
99147
T285
S
I
G
L
L
D
M
T
K
E
K
E
F
Y
D
Chimpanzee
Pan troglodytes
XP_001148438
858
99157
T285
S
I
G
L
L
D
M
T
K
E
K
E
F
Y
D
Rhesus Macaque
Macaca mulatta
XP_001092604
858
99206
T285
S
I
G
L
L
D
M
T
K
E
K
E
F
Y
D
Dog
Lupus familis
XP_543934
846
97567
T270
S
I
G
L
L
D
M
T
K
E
K
E
F
Y
D
Cat
Felis silvestris
Mouse
Mus musculus
Q91ZQ1
861
98767
T285
S
I
G
L
L
D
M
T
K
E
K
E
F
Y
D
Rat
Rattus norvegicus
Q8VID6
935
104553
R385
A
S
R
K
E
Y
E
R
S
R
A
L
L
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506083
861
99448
T283
S
V
G
L
L
D
M
T
K
Q
K
E
F
F
D
Chicken
Gallus gallus
P52731
862
99990
T285
S
V
G
L
L
D
M
T
K
E
K
E
F
Y
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_957165
852
98238
T281
S
C
G
L
L
D
M
T
K
E
K
E
F
Y
D
Tiger Blowfish
Takifugu rubipres
Q1KKS3
903
102001
R339
A
S
R
K
E
Y
D
R
S
R
A
L
L
E
V
Fruit Fly
Dros. melanogaster
Q9VFI9
1131
125621
D473
S
V
F
L
V
D
L
D
C
C
E
A
S
H
L
Honey Bee
Apis mellifera
XP_394107
1016
115998
D412
A
V
Y
L
L
D
L
D
C
G
E
A
G
H
L
Nematode Worm
Caenorhab. elegans
P91119
710
81117
K216
E
N
I
A
K
Q
R
K
L
S
N
F
L
L
D
Sea Urchin
Strong. purpuratus
NP_001029121
949
108476
T362
M
V
F
I
L
E
T
T
E
E
S
Y
L
P
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.7
88.5
N.A.
86.5
23.8
N.A.
62.9
82.7
N.A.
69.4
24.2
23.7
25.3
22.9
33.3
Protein Similarity:
100
99.8
99.6
94
N.A.
93.9
45
N.A.
80
91.6
N.A.
82.5
43.1
40.3
44.1
41.3
53.6
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
80
93.3
N.A.
93.3
0
20
20
6.6
20
P-Site Similarity:
100
100
100
100
N.A.
100
6.6
N.A.
100
100
N.A.
93.3
6.6
53.3
53.3
6.6
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
0
0
8
0
0
0
0
0
0
15
15
0
0
8
% A
% Cys:
0
8
0
0
0
0
0
0
15
8
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
72
8
15
0
0
0
0
0
0
65
% D
% Glu:
8
0
0
0
15
8
8
0
8
58
15
58
0
15
0
% E
% Phe:
0
0
15
0
0
0
0
0
0
0
0
8
58
8
0
% F
% Gly:
0
0
58
0
0
0
0
0
0
8
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% H
% Ile:
0
36
8
8
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
15
8
0
0
8
58
0
58
0
0
0
0
% K
% Leu:
0
0
0
72
72
0
15
0
8
0
0
15
29
8
15
% L
% Met:
8
0
0
0
0
0
58
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% Q
% Arg:
0
0
15
0
0
0
8
15
0
15
0
0
0
0
0
% R
% Ser:
65
15
0
0
0
0
0
0
15
8
8
0
8
0
0
% S
% Thr:
0
0
0
0
0
0
8
65
0
0
0
0
0
0
0
% T
% Val:
0
36
0
0
8
0
0
0
0
0
0
0
0
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
15
0
0
0
0
0
8
0
50
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _