KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDE6C
All Species:
30.61
Human Site:
T463
Identified Species:
51.79
UniProt:
P51160
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51160
NP_006195.3
858
99147
T463
L
M
N
Q
T
K
A
T
P
E
E
I
K
S
I
Chimpanzee
Pan troglodytes
XP_001148438
858
99157
T463
L
M
N
Q
T
K
A
T
P
E
E
I
K
S
I
Rhesus Macaque
Macaca mulatta
XP_001092604
858
99206
T463
L
M
N
Q
T
K
A
T
P
E
E
I
K
S
I
Dog
Lupus familis
XP_543934
846
97567
T448
L
M
S
Q
T
K
A
T
P
D
E
I
K
S
I
Cat
Felis silvestris
Mouse
Mus musculus
Q91ZQ1
861
98767
T463
V
M
N
L
T
K
A
T
P
D
E
I
S
S
I
Rat
Rattus norvegicus
Q8VID6
935
104553
H584
A
L
D
V
L
S
Y
H
A
T
C
S
K
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506083
861
99448
S461
V
K
Y
H
V
K
C
S
N
D
E
I
Q
E
I
Chicken
Gallus gallus
P52731
862
99990
T463
L
M
Y
Q
T
K
A
T
P
T
E
V
E
S
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_957165
852
98238
T459
V
M
Y
Q
T
K
A
T
P
A
E
V
Q
Q
I
Tiger Blowfish
Takifugu rubipres
Q1KKS3
903
102001
H538
A
L
D
V
L
S
Y
H
A
T
C
S
K
T
E
Fruit Fly
Dros. melanogaster
Q9VFI9
1131
125621
S649
K
V
A
L
E
C
L
S
Y
H
A
T
A
S
Q
Honey Bee
Apis mellifera
XP_394107
1016
115998
Y585
V
A
L
E
C
L
S
Y
H
A
T
A
S
N
D
Nematode Worm
Caenorhab. elegans
P91119
710
81117
K385
G
L
A
L
H
H
A
K
L
Y
D
K
I
R
R
Sea Urchin
Strong. purpuratus
NP_001029121
949
108476
Y537
V
A
L
D
V
L
S
Y
H
A
T
A
Q
P
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.7
88.5
N.A.
86.5
23.8
N.A.
62.9
82.7
N.A.
69.4
24.2
23.7
25.3
22.9
33.3
Protein Similarity:
100
99.8
99.6
94
N.A.
93.9
45
N.A.
80
91.6
N.A.
82.5
43.1
40.3
44.1
41.3
53.6
P-Site Identity:
100
100
100
86.6
N.A.
73.3
6.6
N.A.
26.6
73.3
N.A.
60
6.6
6.6
0
6.6
0
P-Site Similarity:
100
100
100
100
N.A.
86.6
26.6
N.A.
53.3
86.6
N.A.
80
26.6
20
26.6
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
15
15
0
0
0
58
0
15
22
8
15
8
8
0
% A
% Cys:
0
0
0
0
8
8
8
0
0
0
15
0
0
0
0
% C
% Asp:
0
0
15
8
0
0
0
0
0
22
8
0
0
0
15
% D
% Glu:
0
0
0
8
8
0
0
0
0
22
58
0
8
8
15
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
8
8
8
0
15
15
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
43
8
0
58
% I
% Lys:
8
8
0
0
0
58
0
8
0
0
0
8
43
0
0
% K
% Leu:
36
22
15
22
15
15
8
0
8
0
0
0
0
0
0
% L
% Met:
0
50
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
29
0
0
0
0
0
8
0
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
50
0
0
0
0
8
0
% P
% Gln:
0
0
0
43
0
0
0
0
0
0
0
0
22
8
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% R
% Ser:
0
0
8
0
0
15
15
15
0
0
0
15
15
50
0
% S
% Thr:
0
0
0
0
50
0
0
50
0
22
15
8
0
8
0
% T
% Val:
36
8
0
15
15
0
0
0
0
0
0
15
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
22
0
0
0
15
15
8
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _