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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCNN1D
All Species:
4.55
Human Site:
S576
Identified Species:
10
UniProt:
P51172
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51172
NP_001123885.1
638
70215
S576
W
F
S
W
P
R
A
S
P
A
S
G
A
S
S
Chimpanzee
Pan troglodytes
O46547
638
70169
S576
W
F
S
W
P
R
A
S
P
A
S
G
A
S
S
Rhesus Macaque
Macaca mulatta
XP_001103409
726
81639
R657
W
S
P
G
R
G
D
R
G
A
Q
E
V
A
S
Dog
Lupus familis
XP_546718
606
68405
W547
A
L
L
L
G
C
R
W
L
R
R
V
Q
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q61180
699
78875
R627
W
S
P
G
R
G
A
R
G
A
R
E
V
A
S
Rat
Rattus norvegicus
P37089
698
78869
R627
W
S
P
G
R
G
A
R
G
A
R
E
V
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514879
426
48716
C367
M
Q
A
C
L
H
S
C
F
Q
Q
L
L
I
E
Chicken
Gallus gallus
Q92075
637
73218
Q578
F
R
W
F
R
S
K
Q
W
H
S
S
P
A
P
Frog
Xenopus laevis
P51167
632
72609
P561
G
E
E
T
T
V
V
P
T
P
A
P
A
F
A
Zebra Danio
Brachydanio rerio
Q708S3
558
62430
N499
E
Q
I
Q
R
T
K
N
L
R
E
Q
N
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09274
887
100314
H737
S
I
S
A
Q
S
H
H
S
V
P
V
H
R
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
34.2
62.8
N.A.
34.4
34.9
N.A.
37.7
37.7
36.3
21.1
N.A.
N.A.
N.A.
22.2
N.A.
Protein Similarity:
100
99.2
51.3
71.4
N.A.
52.6
52.1
N.A.
45.9
56.5
56.4
36.8
N.A.
N.A.
N.A.
36.2
N.A.
P-Site Identity:
100
100
20
0
N.A.
26.6
26.6
N.A.
0
6.6
6.6
0
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
26.6
6.6
N.A.
33.3
33.3
N.A.
13.3
26.6
20
6.6
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
10
0
0
37
0
0
46
10
0
28
46
19
% A
% Cys:
0
0
0
10
0
10
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
10
10
10
0
0
0
0
0
0
0
10
28
0
0
10
% E
% Phe:
10
19
0
10
0
0
0
0
10
0
0
0
0
10
0
% F
% Gly:
10
0
0
28
10
28
0
0
28
0
0
19
0
0
0
% G
% His:
0
0
0
0
0
10
10
10
0
10
0
0
10
0
0
% H
% Ile:
0
10
10
0
0
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
0
0
0
0
0
0
19
0
0
0
0
0
0
0
10
% K
% Leu:
0
10
10
10
10
0
0
0
19
0
0
10
10
10
0
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% N
% Pro:
0
0
28
0
19
0
0
10
19
10
10
10
10
0
19
% P
% Gln:
0
19
0
10
10
0
0
10
0
10
19
10
10
0
0
% Q
% Arg:
0
10
0
0
46
19
10
28
0
19
28
0
0
10
0
% R
% Ser:
10
28
28
0
0
19
10
19
10
0
28
10
0
19
46
% S
% Thr:
0
0
0
10
10
10
0
0
10
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
10
10
0
0
10
0
19
28
0
0
% V
% Trp:
46
0
10
19
0
0
0
10
10
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _