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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SCNN1D All Species: 8.79
Human Site: T27 Identified Species: 19.33
UniProt: P51172 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51172 NP_001123885.1 638 70215 T27 H L Q A A A Q T P P R P G P P
Chimpanzee Pan troglodytes O46547 638 70169 T27 H L Q A A A Q T P P R P G P P
Rhesus Macaque Macaca mulatta XP_001103409 726 81639 S69 K L E E Q D A S P P Q P T P G
Dog Lupus familis XP_546718 606 68405 Q27 P L P E D R R Q E R L V E L H
Cat Felis silvestris
Mouse Mus musculus Q61180 699 78875 G28 S P K G S M K G N N F K E Q D
Rat Rattus norvegicus P37089 698 78869 G28 S P K G S M K G N Q F K E Q D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514879 426 48716
Chicken Gallus gallus Q92075 637 73218 T28 T R Q C K Q E T E Q Q Q K E D
Frog Xenopus laevis P51167 632 72609 S28 E L F E F F C S N T T I H G A
Zebra Danio Brachydanio rerio Q708S3 558 62430
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09274 887 100314 L36 K P S P M S I L M P H L M V G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 34.2 62.8 N.A. 34.4 34.9 N.A. 37.7 37.7 36.3 21.1 N.A. N.A. N.A. 22.2 N.A.
Protein Similarity: 100 99.2 51.3 71.4 N.A. 52.6 52.1 N.A. 45.9 56.5 56.4 36.8 N.A. N.A. N.A. 36.2 N.A.
P-Site Identity: 100 100 33.3 6.6 N.A. 0 0 N.A. 0 13.3 6.6 0 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 100 53.3 13.3 N.A. 20 20 N.A. 0 26.6 13.3 0 N.A. N.A. N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 19 19 19 10 0 0 0 0 0 0 0 10 % A
% Cys: 0 0 0 10 0 0 10 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 10 10 0 0 0 0 0 0 0 0 28 % D
% Glu: 10 0 10 28 0 0 10 0 19 0 0 0 28 10 0 % E
% Phe: 0 0 10 0 10 10 0 0 0 0 19 0 0 0 0 % F
% Gly: 0 0 0 19 0 0 0 19 0 0 0 0 19 10 19 % G
% His: 19 0 0 0 0 0 0 0 0 0 10 0 10 0 10 % H
% Ile: 0 0 0 0 0 0 10 0 0 0 0 10 0 0 0 % I
% Lys: 19 0 19 0 10 0 19 0 0 0 0 19 10 0 0 % K
% Leu: 0 46 0 0 0 0 0 10 0 0 10 10 0 10 0 % L
% Met: 0 0 0 0 10 19 0 0 10 0 0 0 10 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 28 10 0 0 0 0 0 % N
% Pro: 10 28 10 10 0 0 0 0 28 37 0 28 0 28 19 % P
% Gln: 0 0 28 0 10 10 19 10 0 19 19 10 0 19 0 % Q
% Arg: 0 10 0 0 0 10 10 0 0 10 19 0 0 0 0 % R
% Ser: 19 0 10 0 19 10 0 19 0 0 0 0 0 0 0 % S
% Thr: 10 0 0 0 0 0 0 28 0 10 10 0 10 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 10 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _