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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCD1
All Species:
16.67
Human Site:
S224
Identified Species:
30.56
UniProt:
P51178
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51178
NP_001124436.1
756
85665
S224
T
F
A
E
A
A
G
S
G
E
T
L
S
V
D
Chimpanzee
Pan troglodytes
XP_001142960
788
88666
E266
I
F
H
Q
Y
S
G
E
D
R
V
L
S
A
P
Rhesus Macaque
Macaca mulatta
XP_001089399
777
88189
S245
T
F
A
E
A
A
G
S
G
E
T
L
S
V
D
Dog
Lupus familis
XP_859460
756
85972
S224
T
F
A
E
A
A
G
S
G
E
T
L
S
V
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3B1
756
85883
S224
A
F
A
E
A
A
G
S
A
E
T
L
S
V
E
Rat
Rattus norvegicus
P10688
756
85944
S224
A
F
E
E
A
A
G
S
A
E
T
L
S
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514368
738
83813
Q217
L
S
V
D
R
L
V
Q
F
L
R
L
E
Q
K
Chicken
Gallus gallus
Q2VRL0
637
72514
I168
H
P
L
C
D
Y
F
I
S
S
S
H
N
T
Y
Frog
Xenopus laevis
Q32NH8
758
87399
D218
I
F
Q
D
F
S
K
D
G
K
K
L
T
L
L
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
N243
V
F
R
H
Y
S
G
N
G
C
V
L
T
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001008790
753
85559
D227
V
F
K
K
Y
S
G
D
D
D
Y
W
T
P
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q944C2
578
66234
K109
L
N
H
P
I
D
S
K
V
H
Q
D
M
A
S
Baker's Yeast
Sacchar. cerevisiae
P32383
869
100529
L226
E
L
M
E
S
I
L
L
P
D
N
S
Q
F
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.3
95.3
93.9
N.A.
91
91.2
N.A.
66.4
38.7
51.3
47.1
N.A.
N.A.
N.A.
N.A.
41.9
Protein Similarity:
100
64.2
96
96.3
N.A.
94.5
94.4
N.A.
79.3
53.3
67.9
64.8
N.A.
N.A.
N.A.
N.A.
63.2
P-Site Identity:
100
26.6
100
100
N.A.
80
73.3
N.A.
6.6
0
20
26.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
40
100
100
N.A.
86.6
80
N.A.
13.3
13.3
53.3
46.6
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
23
24.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.7
42.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
31
0
39
39
0
0
16
0
0
0
0
16
8
% A
% Cys:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
0
16
8
8
0
16
16
16
0
8
0
0
24
% D
% Glu:
8
0
8
47
0
0
0
8
0
39
0
0
8
0
24
% E
% Phe:
0
70
0
0
8
0
8
0
8
0
0
0
0
8
0
% F
% Gly:
0
0
0
0
0
0
62
0
39
0
0
0
0
0
0
% G
% His:
8
0
16
8
0
0
0
0
0
8
0
8
0
0
0
% H
% Ile:
16
0
0
0
8
8
0
8
0
0
0
0
0
0
0
% I
% Lys:
0
0
8
8
0
0
8
8
0
8
8
0
0
0
8
% K
% Leu:
16
8
8
0
0
8
8
8
0
8
0
70
0
8
16
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
8
0
0
0
0
0
8
0
0
8
0
8
0
0
% N
% Pro:
0
8
0
8
0
0
0
0
8
0
0
0
0
8
8
% P
% Gln:
0
0
8
8
0
0
0
8
0
0
8
0
8
8
0
% Q
% Arg:
0
0
8
0
8
0
0
0
0
8
8
0
0
0
0
% R
% Ser:
0
8
0
0
8
31
8
39
8
8
8
8
47
0
8
% S
% Thr:
24
0
0
0
0
0
0
0
0
0
39
0
24
16
0
% T
% Val:
16
0
8
0
0
0
8
0
8
0
16
0
0
39
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
24
8
0
0
0
0
8
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _