KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCD1
All Species:
34.24
Human Site:
S325
Identified Species:
62.78
UniProt:
P51178
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51178
NP_001124436.1
756
85665
S325
D
Q
L
A
G
P
S
S
T
E
A
Y
I
R
A
Chimpanzee
Pan troglodytes
XP_001142960
788
88666
S366
S
Q
I
G
G
P
S
S
T
E
A
Y
V
R
A
Rhesus Macaque
Macaca mulatta
XP_001089399
777
88189
S346
D
Q
L
A
G
P
S
S
T
E
A
Y
I
R
A
Dog
Lupus familis
XP_859460
756
85972
S325
D
Q
L
T
G
P
S
S
T
E
A
Y
I
R
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3B1
756
85883
S325
D
Q
L
T
G
P
S
S
T
E
A
Y
I
R
A
Rat
Rattus norvegicus
P10688
756
85944
S325
D
Q
L
T
G
P
S
S
T
E
A
Y
I
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514368
738
83813
R316
A
Y
I
R
A
L
S
R
G
C
R
C
V
E
L
Chicken
Gallus gallus
Q2VRL0
637
72514
L266
Q
E
R
I
A
Q
Y
L
L
N
I
L
G
D
K
Frog
Xenopus laevis
Q32NH8
758
87399
S319
D
Q
I
R
G
Q
S
S
I
E
G
Y
I
R
A
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
S342
D
Q
V
T
S
A
S
S
T
E
P
Y
I
R
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001008790
753
85559
S328
D
Q
L
R
G
P
S
S
T
E
A
Y
I
S
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q944C2
578
66234
E207
Y
P
V
I
L
T
L
E
D
H
L
T
P
D
L
Baker's Yeast
Sacchar. cerevisiae
P32383
869
100529
S409
K
Q
I
A
E
T
P
S
V
E
G
Y
I
Q
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.3
95.3
93.9
N.A.
91
91.2
N.A.
66.4
38.7
51.3
47.1
N.A.
N.A.
N.A.
N.A.
41.9
Protein Similarity:
100
64.2
96
96.3
N.A.
94.5
94.4
N.A.
79.3
53.3
67.9
64.8
N.A.
N.A.
N.A.
N.A.
63.2
P-Site Identity:
100
73.3
100
93.3
N.A.
93.3
93.3
N.A.
6.6
0
66.6
66.6
N.A.
N.A.
N.A.
N.A.
86.6
P-Site Similarity:
100
86.6
100
93.3
N.A.
93.3
93.3
N.A.
20
6.6
73.3
73.3
N.A.
N.A.
N.A.
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
23
24.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.7
42.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
24
16
8
0
0
0
0
54
0
0
0
70
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% C
% Asp:
62
0
0
0
0
0
0
0
8
0
0
0
0
16
0
% D
% Glu:
0
8
0
0
8
0
0
8
0
77
0
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
62
0
0
0
8
0
16
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
31
16
0
0
0
0
8
0
8
0
70
0
0
% I
% Lys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% K
% Leu:
0
0
47
0
8
8
8
8
8
0
8
8
0
0
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
8
0
0
0
54
8
0
0
0
8
0
8
0
0
% P
% Gln:
8
77
0
0
0
16
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
8
24
0
0
0
8
0
0
8
0
0
62
0
% R
% Ser:
8
0
0
0
8
0
77
77
0
0
0
0
0
8
0
% S
% Thr:
0
0
0
31
0
16
0
0
62
0
0
8
0
0
0
% T
% Val:
0
0
16
0
0
0
0
0
8
0
0
0
16
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
0
0
0
8
0
0
0
0
77
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _