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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLCD1 All Species: 14.24
Human Site: S34 Identified Species: 26.11
UniProt: P51178 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51178 NP_001124436.1 756 85665 S34 Q L L K V K S S S W R R E R F
Chimpanzee Pan troglodytes XP_001142960 788 88666 R77 R L R K I R S R T W H K E R L
Rhesus Macaque Macaca mulatta XP_001089399 777 88189 S55 Q L L K V K S S S W R R E R F
Dog Lupus familis XP_859460 756 85972 N34 Q L L K V K S N S W R R E R F
Cat Felis silvestris
Mouse Mus musculus Q8R3B1 756 85883 S34 Q L L K V K S S S W R R E R F
Rat Rattus norvegicus P10688 756 85944 S34 Q L L K V K S S S W R R E R F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514368 738 83813 F35 G S W R K D R F Y K L Q E D C
Chicken Gallus gallus Q2VRL0 637 72514
Frog Xenopus laevis Q32NH8 758 87399 W32 R K V K S R S W K K Q R Y F K
Zebra Danio Brachydanio rerio A5D6R3 784 89362 Q52 K M M K V R S Q R W R K D R R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_001008790 753 85559 F36 T K K H G R T F S L T D D G T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q944C2 578 66234
Baker's Yeast Sacchar. cerevisiae P32383 869 100529 S39 D D A L D F I S Y S S F Q S S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 47.3 95.3 93.9 N.A. 91 91.2 N.A. 66.4 38.7 51.3 47.1 N.A. N.A. N.A. N.A. 41.9
Protein Similarity: 100 64.2 96 96.3 N.A. 94.5 94.4 N.A. 79.3 53.3 67.9 64.8 N.A. N.A. N.A. N.A. 63.2
P-Site Identity: 100 40 100 93.3 N.A. 100 100 N.A. 6.6 0 20 40 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 73.3 100 100 N.A. 100 100 N.A. 20 0 46.6 80 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 23 24.9 N.A.
Protein Similarity: N.A. N.A. N.A. 37.7 42.8 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 8 8 0 0 8 8 0 0 0 0 0 8 16 8 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 54 0 0 % E
% Phe: 0 0 0 0 0 8 0 16 0 0 0 8 0 8 39 % F
% Gly: 8 0 0 0 8 0 0 0 0 0 0 0 0 8 0 % G
% His: 0 0 0 8 0 0 0 0 0 0 8 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 8 0 0 0 0 0 0 0 0 % I
% Lys: 8 16 8 62 8 39 0 0 8 16 0 16 0 0 8 % K
% Leu: 0 47 39 8 0 0 0 0 0 8 8 0 0 0 8 % L
% Met: 0 8 8 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 39 0 0 0 0 0 0 8 0 0 8 8 8 0 0 % Q
% Arg: 16 0 8 8 0 31 8 8 8 0 47 47 0 54 8 % R
% Ser: 0 8 0 0 8 0 62 39 47 8 8 0 0 8 8 % S
% Thr: 8 0 0 0 0 0 8 0 8 0 8 0 0 0 8 % T
% Val: 0 0 8 0 47 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 8 0 0 0 0 8 0 54 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 16 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _