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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCD1
All Species:
24.85
Human Site:
S637
Identified Species:
45.56
UniProt:
P51178
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51178
NP_001124436.1
756
85665
S637
R
L
N
I
R
V
I
S
G
Q
Q
L
P
K
V
Chimpanzee
Pan troglodytes
XP_001142960
788
88666
A668
L
S
I
Q
V
L
T
A
Q
Q
L
P
K
L
N
Rhesus Macaque
Macaca mulatta
XP_001089399
777
88189
S658
R
L
N
I
R
V
I
S
G
Q
Q
L
P
K
V
Dog
Lupus familis
XP_859460
756
85972
S637
R
L
S
I
R
V
I
S
G
Q
Q
L
P
K
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3B1
756
85883
S637
K
L
R
V
W
I
I
S
G
Q
Q
L
P
K
V
Rat
Rattus norvegicus
P10688
756
85944
S637
R
L
R
V
R
I
I
S
G
Q
Q
L
P
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514368
738
83813
S618
K
L
S
I
L
V
I
S
G
Q
Q
L
P
K
V
Chicken
Gallus gallus
Q2VRL0
637
72514
P525
I
S
G
H
Q
L
P
P
S
N
L
S
K
S
N
Frog
Xenopus laevis
Q32NH8
758
87399
A631
L
S
I
L
V
I
S
A
Q
Q
L
P
K
V
E
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
A650
L
T
I
R
V
I
S
A
Q
Q
L
P
K
I
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001008790
753
85559
V633
T
Q
H
V
T
L
T
V
I
S
G
Q
Q
L
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q944C2
578
66234
Q466
K
G
W
D
S
G
F
Q
R
T
C
F
N
T
W
Baker's Yeast
Sacchar. cerevisiae
P32383
869
100529
S741
T
V
K
I
R
I
L
S
T
Q
L
L
P
R
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.3
95.3
93.9
N.A.
91
91.2
N.A.
66.4
38.7
51.3
47.1
N.A.
N.A.
N.A.
N.A.
41.9
Protein Similarity:
100
64.2
96
96.3
N.A.
94.5
94.4
N.A.
79.3
53.3
67.9
64.8
N.A.
N.A.
N.A.
N.A.
63.2
P-Site Identity:
100
6.6
100
93.3
N.A.
66.6
80
N.A.
80
0
6.6
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
20
100
100
N.A.
86.6
93.3
N.A.
93.3
13.3
26.6
20
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
23
24.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.7
42.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
24
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% F
% Gly:
0
8
8
0
0
8
0
0
47
0
8
0
0
0
0
% G
% His:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
24
39
0
39
47
0
8
0
0
0
0
8
0
% I
% Lys:
24
0
8
0
0
0
0
0
0
0
0
0
31
47
0
% K
% Leu:
24
47
0
8
8
24
8
0
0
0
39
54
0
16
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
16
0
0
0
0
0
0
8
0
0
8
0
24
% N
% Pro:
0
0
0
0
0
0
8
8
0
0
0
24
54
0
8
% P
% Gln:
0
8
0
8
8
0
0
8
24
77
47
8
8
0
0
% Q
% Arg:
31
0
16
8
39
0
0
0
8
0
0
0
0
8
0
% R
% Ser:
0
24
16
0
8
0
16
54
8
8
0
8
0
8
0
% S
% Thr:
16
8
0
0
8
0
16
0
8
8
0
0
0
8
0
% T
% Val:
0
8
0
24
24
31
0
8
0
0
0
0
0
8
47
% V
% Trp:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _