KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCD1
All Species:
23.94
Human Site:
T209
Identified Species:
43.89
UniProt:
P51178
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51178
NP_001124436.1
756
85665
T209
E
A
F
Y
K
M
L
T
Q
R
V
E
I
D
R
Chimpanzee
Pan troglodytes
XP_001142960
788
88666
L251
E
E
F
L
R
R
L
L
K
R
P
E
L
E
E
Rhesus Macaque
Macaca mulatta
XP_001089399
777
88189
T230
E
A
F
Y
K
M
L
T
Q
R
V
E
I
D
R
Dog
Lupus familis
XP_859460
756
85972
T209
E
A
F
Y
K
M
L
T
Q
R
A
E
I
D
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3B1
756
85883
T209
E
T
F
Y
R
M
L
T
Q
R
V
E
I
D
R
Rat
Rattus norvegicus
P10688
756
85944
T209
E
T
F
Y
K
M
L
T
Q
R
A
E
I
D
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514368
738
83813
S202
E
I
D
E
I
F
Q
S
I
A
G
S
A
D
T
Chicken
Gallus gallus
Q2VRL0
637
72514
R153
T
I
F
K
K
E
H
R
T
V
Y
Q
D
M
N
Frog
Xenopus laevis
Q32NH8
758
87399
T203
V
L
F
Y
K
A
L
T
Q
R
D
E
V
L
K
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
M228
E
E
F
C
R
E
M
M
R
R
P
E
L
D
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001008790
753
85559
T212
V
E
F
Y
R
I
I
T
R
R
P
D
L
Q
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q944C2
578
66234
F94
T
L
N
L
D
D
F
F
S
F
L
F
S
D
D
Baker's Yeast
Sacchar. cerevisiae
P32383
869
100529
C211
N
T
F
L
S
C
I
C
G
L
V
K
L
R
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.3
95.3
93.9
N.A.
91
91.2
N.A.
66.4
38.7
51.3
47.1
N.A.
N.A.
N.A.
N.A.
41.9
Protein Similarity:
100
64.2
96
96.3
N.A.
94.5
94.4
N.A.
79.3
53.3
67.9
64.8
N.A.
N.A.
N.A.
N.A.
63.2
P-Site Identity:
100
33.3
100
93.3
N.A.
86.6
86.6
N.A.
13.3
13.3
53.3
33.3
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
60
100
93.3
N.A.
93.3
86.6
N.A.
20
20
66.6
60
N.A.
N.A.
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
23
24.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.7
42.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
24
0
0
0
8
0
0
0
8
16
0
8
0
8
% A
% Cys:
0
0
0
8
0
8
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
8
8
0
0
0
0
8
8
8
62
8
% D
% Glu:
62
24
0
8
0
16
0
0
0
0
0
62
0
8
16
% E
% Phe:
0
0
85
0
0
8
8
8
0
8
0
8
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
16
0
0
8
8
16
0
8
0
0
0
39
0
0
% I
% Lys:
0
0
0
8
47
0
0
0
8
0
0
8
0
0
8
% K
% Leu:
0
16
0
24
0
0
54
8
0
8
8
0
31
8
0
% L
% Met:
0
0
0
0
0
39
8
8
0
0
0
0
0
8
0
% M
% Asn:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
24
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
8
0
47
0
0
8
0
8
0
% Q
% Arg:
0
0
0
0
31
8
0
8
16
70
0
0
0
8
47
% R
% Ser:
0
0
0
0
8
0
0
8
8
0
0
8
8
0
0
% S
% Thr:
16
24
0
0
0
0
0
54
8
0
0
0
0
0
8
% T
% Val:
16
0
0
0
0
0
0
0
0
8
31
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
54
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _