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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCD1
All Species:
25.15
Human Site:
T263
Identified Species:
46.11
UniProt:
P51178
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51178
NP_001124436.1
756
85665
T263
E
R
Y
E
P
S
E
T
A
K
A
Q
R
Q
M
Chimpanzee
Pan troglodytes
XP_001142960
788
88666
T304
Q
T
Y
E
L
N
E
T
A
K
Q
H
E
L
M
Rhesus Macaque
Macaca mulatta
XP_001089399
777
88189
T284
E
R
Y
E
P
S
E
T
A
K
A
Q
R
Q
M
Dog
Lupus familis
XP_859460
756
85972
T263
E
R
Y
E
P
S
E
T
A
K
A
Q
R
Q
M
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3B1
756
85883
T263
E
R
Y
E
P
S
E
T
A
K
A
Q
R
Q
M
Rat
Rattus norvegicus
P10688
756
85944
T263
E
R
Y
E
P
S
E
T
A
K
A
Q
R
Q
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514368
738
83813
D254
E
A
K
E
M
T
K
D
G
F
L
M
Y
L
L
Chicken
Gallus gallus
Q2VRL0
637
72514
D204
G
C
R
C
L
E
I
D
C
W
D
G
S
N
N
Frog
Xenopus laevis
Q32NH8
758
87399
T257
A
R
Y
E
P
S
D
T
A
K
K
L
H
A
M
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
W280
Q
T
F
E
L
N
D
W
A
Q
K
N
L
F
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001008790
753
85559
E266
E
E
Y
E
P
N
Q
E
F
R
D
Q
K
I
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q944C2
578
66234
L145
S
E
C
S
D
V
P
L
I
K
A
L
K
R
G
Baker's Yeast
Sacchar. cerevisiae
P32383
869
100529
Y347
D
R
Q
T
A
W
S
Y
F
I
K
Y
R
E
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.3
95.3
93.9
N.A.
91
91.2
N.A.
66.4
38.7
51.3
47.1
N.A.
N.A.
N.A.
N.A.
41.9
Protein Similarity:
100
64.2
96
96.3
N.A.
94.5
94.4
N.A.
79.3
53.3
67.9
64.8
N.A.
N.A.
N.A.
N.A.
63.2
P-Site Identity:
100
46.6
100
100
N.A.
100
100
N.A.
13.3
0
60
20
N.A.
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
100
60
100
100
N.A.
100
100
N.A.
33.3
0
66.6
53.3
N.A.
N.A.
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
23
24.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.7
42.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
8
0
0
0
62
0
47
0
0
8
0
% A
% Cys:
0
8
8
8
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
8
0
16
16
0
0
16
0
0
0
0
% D
% Glu:
54
16
0
77
0
8
47
8
0
0
0
0
8
8
0
% E
% Phe:
0
0
8
0
0
0
0
0
16
8
0
0
0
8
0
% F
% Gly:
8
0
0
0
0
0
0
0
8
0
0
8
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
8
8
0
0
0
8
0
% I
% Lys:
0
0
8
0
0
0
8
0
0
62
24
0
16
0
0
% K
% Leu:
0
0
0
0
24
0
0
8
0
0
8
16
8
16
16
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
62
% M
% Asn:
0
0
0
0
0
24
0
0
0
0
0
8
0
8
8
% N
% Pro:
0
0
0
0
54
0
8
0
0
0
0
0
0
0
8
% P
% Gln:
16
0
8
0
0
0
8
0
0
8
8
47
0
39
0
% Q
% Arg:
0
54
8
0
0
0
0
0
0
8
0
0
47
8
0
% R
% Ser:
8
0
0
8
0
47
8
0
0
0
0
0
8
0
0
% S
% Thr:
0
16
0
8
0
8
0
54
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
8
0
8
0
8
0
0
0
0
0
% W
% Tyr:
0
0
62
0
0
0
0
8
0
0
0
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _