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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCD1
All Species:
21.52
Human Site:
Y42
Identified Species:
39.44
UniProt:
P51178
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51178
NP_001124436.1
756
85665
Y42
S
W
R
R
E
R
F
Y
K
L
Q
E
D
C
K
Chimpanzee
Pan troglodytes
XP_001142960
788
88666
Y85
T
W
H
K
E
R
L
Y
R
L
Q
E
D
G
L
Rhesus Macaque
Macaca mulatta
XP_001089399
777
88189
Y63
S
W
R
R
E
R
F
Y
K
L
Q
E
D
C
K
Dog
Lupus familis
XP_859460
756
85972
Y42
S
W
R
R
E
R
F
Y
K
L
Q
E
D
C
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3B1
756
85883
Y42
S
W
R
R
E
R
F
Y
K
L
Q
E
D
C
K
Rat
Rattus norvegicus
P10688
756
85944
Y42
S
W
R
R
E
R
F
Y
K
L
Q
E
D
C
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514368
738
83813
K43
Y
K
L
Q
E
D
C
K
T
I
W
Q
E
S
K
Chicken
Gallus gallus
Q2VRL0
637
72514
Frog
Xenopus laevis
Q32NH8
758
87399
L40
K
K
Q
R
Y
F
K
L
Q
E
D
C
M
T
I
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
L60
R
W
R
K
D
R
R
L
K
L
L
E
D
C
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001008790
753
85559
A44
S
L
T
D
D
G
T
A
L
M
Y
T
P
S
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q944C2
578
66234
Baker's Yeast
Sacchar. cerevisiae
P32383
869
100529
F47
Y
S
S
F
Q
S
S
F
N
T
D
Q
K
S
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.3
95.3
93.9
N.A.
91
91.2
N.A.
66.4
38.7
51.3
47.1
N.A.
N.A.
N.A.
N.A.
41.9
Protein Similarity:
100
64.2
96
96.3
N.A.
94.5
94.4
N.A.
79.3
53.3
67.9
64.8
N.A.
N.A.
N.A.
N.A.
63.2
P-Site Identity:
100
53.3
100
100
N.A.
100
100
N.A.
13.3
0
6.6
53.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
73.3
100
100
N.A.
100
100
N.A.
40
0
20
66.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
23
24.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.7
42.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
8
0
47
0
% C
% Asp:
0
0
0
8
16
8
0
0
0
0
16
0
54
0
0
% D
% Glu:
0
0
0
0
54
0
0
0
0
8
0
54
8
0
0
% E
% Phe:
0
0
0
8
0
8
39
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% I
% Lys:
8
16
0
16
0
0
8
8
47
0
0
0
8
0
54
% K
% Leu:
0
8
8
0
0
0
8
16
8
54
8
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
0
0
8
8
8
0
0
0
8
0
47
16
0
0
0
% Q
% Arg:
8
0
47
47
0
54
8
0
8
0
0
0
0
0
0
% R
% Ser:
47
8
8
0
0
8
8
0
0
0
0
0
0
24
0
% S
% Thr:
8
0
8
0
0
0
8
0
8
8
0
8
0
8
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% V
% Trp:
0
54
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
16
0
0
0
8
0
0
47
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _