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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RORC
All Species:
10.91
Human Site:
Y186
Identified Species:
34.29
UniProt:
P51449
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51449
NP_001001523.1
518
58195
Y186
A
S
G
S
G
P
S
Y
S
N
N
L
A
K
A
Chimpanzee
Pan troglodytes
XP_001173390
504
57336
E176
I
S
A
N
G
L
T
E
L
H
D
D
L
S
N
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_540323
518
58055
Y186
A
P
G
S
G
S
S
Y
P
S
S
L
A
K
A
Cat
Felis silvestris
Mouse
Mus musculus
P51450
516
58099
Y184
A
S
G
S
G
P
P
Y
S
N
T
L
A
K
T
Rat
Rattus norvegicus
P45446
470
53182
G172
G
Y
Y
N
I
D
S
G
Q
P
S
P
D
Q
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510767
545
62219
T211
L
T
P
T
Y
N
I
T
T
N
G
L
T
E
L
Chicken
Gallus gallus
XP_413763
696
76277
T362
L
T
P
T
Y
N
I
T
T
N
G
L
T
E
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P31396
487
55266
V198
P
Y
G
Y
S
A
S
V
T
P
Q
Q
T
M
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.1
N.A.
85.5
N.A.
88.8
47
N.A.
33
30.6
N.A.
N.A.
N.A.
35.7
N.A.
N.A.
N.A.
Protein Similarity:
100
66.4
N.A.
90.1
N.A.
93
63.9
N.A.
51
44.5
N.A.
N.A.
N.A.
52.9
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
N.A.
66.6
N.A.
80
6.6
N.A.
13.3
13.3
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
40
N.A.
80
N.A.
80
33.3
N.A.
40
40
N.A.
N.A.
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
38
0
13
0
0
13
0
0
0
0
0
0
38
0
25
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
13
0
0
0
0
13
13
13
0
0
% D
% Glu:
0
0
0
0
0
0
0
13
0
0
0
0
0
25
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
13
0
50
0
50
0
0
13
0
0
25
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% H
% Ile:
13
0
0
0
13
0
25
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
38
0
% K
% Leu:
25
0
0
0
0
13
0
0
13
0
0
63
13
0
25
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% M
% Asn:
0
0
0
25
0
25
0
0
0
50
13
0
0
0
13
% N
% Pro:
13
13
25
0
0
25
13
0
13
25
0
13
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
13
0
13
13
0
13
13
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
38
0
38
13
13
50
0
25
13
25
0
0
13
13
% S
% Thr:
0
25
0
25
0
0
13
25
38
0
13
0
38
0
13
% T
% Val:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
25
13
13
25
0
0
38
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _