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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUSP3
All Species:
15.15
Human Site:
S27
Identified Species:
27.78
UniProt:
P51452
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51452
NP_004081.1
185
20478
S27
S
G
C
Y
S
L
P
S
Q
P
C
N
E
V
T
Chimpanzee
Pan troglodytes
P0C594
220
25358
Y52
F
W
K
G
S
P
Q
Y
T
H
V
N
E
V
W
Rhesus Macaque
Macaca mulatta
XP_001113728
144
16144
G24
H
V
L
N
A
A
E
G
R
S
F
M
H
V
N
Dog
Lupus familis
XP_537624
228
25143
S70
S
G
C
Y
S
L
P
S
Q
P
C
K
E
V
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9D7X3
185
20454
S27
S
G
C
Y
S
L
P
S
Q
P
C
N
E
V
V
Rat
Rattus norvegicus
P0C595
215
24055
Y51
F
W
K
G
S
P
Q
Y
T
H
V
N
E
V
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506876
252
28589
S95
R
L
L
L
E
H
R
S
S
L
G
H
V
N
E
Chicken
Gallus gallus
P0C597
214
24304
P42
R
L
F
W
K
G
C
P
K
Y
T
H
V
N
E
Frog
Xenopus laevis
Q4KL92
209
23732
Y43
F
W
H
G
A
P
K
Y
T
H
V
N
E
V
W
Zebra Danio
Brachydanio rerio
Q29RA3
189
21985
Y31
F
T
H
G
G
V
A
Y
T
H
V
N
E
V
W
Tiger Blowfish
Takifugu rubipres
P0C599
210
23683
Y44
W
S
G
P
G
V
Q
Y
T
H
V
N
Q
V
W
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624869
211
24264
D55
E
Y
Y
R
I
Q
Q
D
I
D
C
D
E
V
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791989
192
21775
Q29
S
I
V
I
A
L
P
Q
R
Q
I
D
E
V
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
37.7
77.8
79.3
N.A.
92.9
39.5
N.A.
33.3
34.5
36.3
40.2
42.8
N.A.
40.7
N.A.
45.8
Protein Similarity:
100
55.4
77.8
79.8
N.A.
96.2
56.7
N.A.
47.2
51.4
54.5
57.1
57.6
N.A.
58.2
N.A.
64
P-Site Identity:
100
26.6
6.6
93.3
N.A.
93.3
26.6
N.A.
6.6
0
20
20
13.3
N.A.
20
N.A.
33.3
P-Site Similarity:
100
26.6
20
93.3
N.A.
93.3
26.6
N.A.
13.3
20
26.6
26.6
26.6
N.A.
26.6
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
24
8
8
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
24
0
0
0
8
0
0
0
31
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
8
0
16
0
0
0
% D
% Glu:
8
0
0
0
8
0
8
0
0
0
0
0
70
0
16
% E
% Phe:
31
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
0
24
8
31
16
8
0
8
0
0
8
0
0
0
0
% G
% His:
8
0
16
0
0
8
0
0
0
39
0
16
8
0
0
% H
% Ile:
0
8
0
8
8
0
0
0
8
0
8
0
0
0
0
% I
% Lys:
0
0
16
0
8
0
8
0
8
0
0
8
0
0
0
% K
% Leu:
0
16
16
8
0
31
0
0
0
8
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
0
54
0
16
8
% N
% Pro:
0
0
0
8
0
24
31
8
0
24
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
31
8
24
8
0
0
8
0
0
% Q
% Arg:
16
0
0
8
0
0
8
0
16
0
0
0
0
0
0
% R
% Ser:
31
8
0
0
39
0
0
31
8
8
0
0
0
0
0
% S
% Thr:
0
8
0
0
0
0
0
0
39
0
8
0
0
0
16
% T
% Val:
0
8
8
0
0
16
0
0
0
0
39
0
16
85
8
% V
% Trp:
8
24
0
8
0
0
0
0
0
0
0
0
0
0
39
% W
% Tyr:
0
8
8
24
0
0
0
39
0
8
0
0
0
0
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _