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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUSP3
All Species:
16.36
Human Site:
S99
Identified Species:
30
UniProt:
P51452
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51452
NP_004081.1
185
20478
S99
D
T
Q
E
F
N
L
S
A
Y
F
E
R
A
A
Chimpanzee
Pan troglodytes
P0C594
220
25358
F124
P
T
F
D
L
S
V
F
F
Y
P
A
A
A
F
Rhesus Macaque
Macaca mulatta
XP_001113728
144
16144
A96
R
S
P
T
L
V
I
A
Y
L
M
M
R
Q
K
Dog
Lupus familis
XP_537624
228
25143
S142
D
T
Q
E
F
N
L
S
A
Y
F
E
R
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9D7X3
185
20454
S99
D
T
Q
E
F
N
L
S
A
Y
F
E
R
A
T
Rat
Rattus norvegicus
P0C595
215
24055
F123
P
T
F
D
L
S
I
F
F
Y
S
A
A
A
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506876
252
28589
S167
D
S
P
Y
F
D
L
S
P
Y
F
H
P
A
A
Chicken
Gallus gallus
P0C597
214
24304
S114
D
L
P
T
F
K
L
S
Q
F
F
Y
S
A
S
Frog
Xenopus laevis
Q4KL92
209
23732
F115
P
S
F
N
L
S
Q
F
F
Y
P
A
A
Q
F
Zebra Danio
Brachydanio rerio
Q29RA3
189
21985
Q103
T
P
T
F
N
I
S
Q
Y
F
Y
S
A
A
E
Tiger Blowfish
Takifugu rubipres
P0C599
210
23683
Q116
K
P
T
F
N
I
S
Q
F
F
H
P
A
A
Q
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624869
211
24264
S127
D
L
C
S
T
D
I
S
K
Y
F
F
T
I
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791989
192
21775
K101
D
F
P
Q
S
N
I
K
Q
H
F
D
T
A
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
37.7
77.8
79.3
N.A.
92.9
39.5
N.A.
33.3
34.5
36.3
40.2
42.8
N.A.
40.7
N.A.
45.8
Protein Similarity:
100
55.4
77.8
79.8
N.A.
96.2
56.7
N.A.
47.2
51.4
54.5
57.1
57.6
N.A.
58.2
N.A.
64
P-Site Identity:
100
20
6.6
100
N.A.
93.3
20
N.A.
53.3
40
6.6
6.6
6.6
N.A.
33.3
N.A.
26.6
P-Site Similarity:
100
40
26.6
100
N.A.
93.3
40
N.A.
66.6
53.3
20
20
13.3
N.A.
46.6
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
24
0
0
24
39
77
31
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
54
0
0
16
0
16
0
0
0
0
0
8
0
0
0
% D
% Glu:
0
0
0
24
0
0
0
0
0
0
0
24
0
0
8
% E
% Phe:
0
8
24
16
39
0
0
24
31
24
54
8
0
0
31
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
8
8
0
0
0
% H
% Ile:
0
0
0
0
0
16
31
0
0
0
0
0
0
8
0
% I
% Lys:
8
0
0
0
0
8
0
8
8
0
0
0
0
0
8
% K
% Leu:
0
16
0
0
31
0
39
0
0
8
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% M
% Asn:
0
0
0
8
16
31
0
0
0
0
0
0
0
0
0
% N
% Pro:
24
16
31
0
0
0
0
0
8
0
16
8
8
0
0
% P
% Gln:
0
0
24
8
0
0
8
16
16
0
0
0
0
16
8
% Q
% Arg:
8
0
0
0
0
0
0
0
0
0
0
0
31
0
0
% R
% Ser:
0
24
0
8
8
24
16
47
0
0
8
8
8
0
8
% S
% Thr:
8
39
16
16
8
0
0
0
0
0
0
0
16
0
8
% T
% Val:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
16
62
8
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _