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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: INSL3 All Species: 4.55
Human Site: T53 Identified Species: 11.11
UniProt: P51460 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51460 NP_005534.2 131 14472 T53 C G G P R W S T E A R R P A A
Chimpanzee Pan troglodytes Q5CZK3 131 14525 T53 C G G P R W S T E A R R P A A
Rhesus Macaque Macaca mulatta NP_001098046 142 15334 R54 C G G S R W R R S D I L A H E
Dog Lupus familis XP_853484 139 15013 R54 C G G S R W R R S D I L T H E
Cat Felis silvestris
Mouse Mus musculus O09107 122 13567 P48 C G G P R W S P E A T Q P V E
Rat Rattus norvegicus Q9WUK0 128 14092 P48 C G G P R W S P E A T Q P V D
Wallaby Macropus eugenll
Platypus Ornith. anatinus NP_001116160 160 17208 W47 A S C G G S S W K L D P P R V
Chicken Gallus gallus
Frog Xenopus laevis NP_001121360 165 18074 R61 C G G S R W R R N E V L Q A A
Zebra Danio Brachydanio rerio XP_002665868 108 11851 I40 K L C G R E F I R A V I F T C
Tiger Blowfish Takifugu rubipres NP_001092113 120 13064 V37 I I P R D Y G V K L C G R E F
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 23.9 25.1 N.A. 59.5 59.5 N.A. 27.5 N.A. 25.4 32 31.3 N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.2 35.9 37.4 N.A. 64.8 66.4 N.A. 36.2 N.A. 36.9 45.7 43.5 N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 33.3 33.3 N.A. 66.6 66.6 N.A. 13.3 N.A. 46.6 13.3 0 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 33.3 33.3 N.A. 73.3 73.3 N.A. 20 N.A. 46.6 13.3 13.3 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 0 0 0 50 0 0 10 30 30 % A
% Cys: 70 0 20 0 0 0 0 0 0 0 10 0 0 0 10 % C
% Asp: 0 0 0 0 10 0 0 0 0 20 10 0 0 0 10 % D
% Glu: 0 0 0 0 0 10 0 0 40 10 0 0 0 10 30 % E
% Phe: 0 0 0 0 0 0 10 0 0 0 0 0 10 0 10 % F
% Gly: 0 70 70 20 10 0 10 0 0 0 0 10 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 20 0 % H
% Ile: 10 10 0 0 0 0 0 10 0 0 20 10 0 0 0 % I
% Lys: 10 0 0 0 0 0 0 0 20 0 0 0 0 0 0 % K
% Leu: 0 10 0 0 0 0 0 0 0 20 0 30 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % N
% Pro: 0 0 10 40 0 0 0 20 0 0 0 10 50 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 20 10 0 0 % Q
% Arg: 0 0 0 10 80 0 30 30 10 0 20 20 10 10 0 % R
% Ser: 0 10 0 30 0 10 50 0 20 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 20 0 0 20 0 10 10 0 % T
% Val: 0 0 0 0 0 0 0 10 0 0 20 0 0 20 10 % V
% Trp: 0 0 0 0 0 70 0 10 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _