KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MMP16
All Species:
31.21
Human Site:
Y377
Identified Species:
76.3
UniProt:
P51512
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51512
NP_005932.2
607
69521
Y377
N
N
R
V
M
D
G
Y
P
M
Q
I
T
Y
F
Chimpanzee
Pan troglodytes
XP_001136415
624
71471
Y394
N
N
R
V
M
D
G
Y
P
M
Q
I
T
Y
F
Rhesus Macaque
Macaca mulatta
XP_001084085
457
52548
N234
P
W
T
L
G
N
P
N
H
D
G
N
D
L
F
Dog
Lupus familis
XP_544165
595
68106
Y365
N
N
R
V
M
D
G
Y
P
M
Q
I
T
Y
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTR0
607
69664
Y377
N
N
R
V
M
D
G
Y
P
M
Q
I
T
Y
F
Rat
Rattus norvegicus
O35548
607
69605
Y377
N
N
R
V
M
D
G
Y
P
M
Q
I
T
Y
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506645
616
70261
Y386
N
N
R
V
M
D
G
Y
P
M
Q
I
T
Y
F
Chicken
Gallus gallus
NP_990528
608
69394
Y379
N
N
R
V
M
D
G
Y
P
M
Q
I
T
Y
F
Frog
Xenopus laevis
Q10835
469
53622
E246
F
P
V
Y
T
Y
T
E
T
S
R
F
V
L
P
Zebra Danio
Brachydanio rerio
XP_700781
642
73530
Y402
D
N
S
V
V
P
G
Y
P
M
Q
I
S
Y
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.6
71.5
93.5
N.A.
97.6
98
N.A.
89.9
92.2
32.6
69
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
96.9
73.3
95.2
N.A.
99
99
N.A.
93.3
95.2
46.2
79.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
100
100
0
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
100
N.A.
100
100
N.A.
100
100
6.6
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
70
0
0
0
10
0
0
10
0
0
% D
% Glu:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
90
% F
% Gly:
0
0
0
0
10
0
80
0
0
0
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
80
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
10
0
0
0
0
0
0
0
0
0
20
0
% L
% Met:
0
0
0
0
70
0
0
0
0
80
0
0
0
0
0
% M
% Asn:
70
80
0
0
0
10
0
10
0
0
0
10
0
0
0
% N
% Pro:
10
10
0
0
0
10
10
0
80
0
0
0
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
80
0
0
0
0
% Q
% Arg:
0
0
70
0
0
0
0
0
0
0
10
0
0
0
0
% R
% Ser:
0
0
10
0
0
0
0
0
0
10
0
0
10
0
0
% S
% Thr:
0
0
10
0
10
0
10
0
10
0
0
0
70
0
0
% T
% Val:
0
0
10
80
10
0
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
10
0
80
0
0
0
0
0
80
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _